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奈韦拉平在抗逆转录病毒治疗中引起皮疹的临床研究 被引量:4

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摘要 目的分析抗逆转录病毒治疗艾滋病中,使用奈韦拉平发生皮疹的情况及皮疹发生后的应对措施。方法将85例艾滋病患者按治疗方案分为A组45例和B组40例,A组予以齐多夫定+拉米夫定+奈韦拉平抗病毒方案,B组予以齐多夫定+拉米夫定+依非韦伦抗病毒方案,分析皮疹的发生特点。结果 A组皮疹发生率为37.8%,高于B组的10.0%;初始治疗时CD4+细胞计数>200个/μl患者的皮疹发生率为58.8%,高于初始治疗时CD4+细胞计数<200个/μl患者的25.0%,差异均有统计学意义(P<0.05)。男性患者的皮疹发生率为30.8%,女性为47.4%,差异无统计学意义(P>0.05)。结论服用奈韦拉平皮疹的发生率高于依非韦伦,皮疹的发生与初始治疗时CD4+细胞计数水平有关,但与性别无关。
出处 《临床合理用药杂志》 2013年第8期49-50,共2页 Chinese Journal of Clinical Rational Drug Use
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