摘要
目的探讨低分子肝素联合硫酸镁治疗重度子痫前期的疗效。方法选择2011年3月～2012年2月在本院治疗的46例诊断为重度子痫前期的患者,随机分为实验组和对照组,每组23例,实验组给予低分子肝素联合硫酸镁治疗,而对照组给予硫酸镁治疗,分析两组患者的期待治疗时间,凝血功能变化,血压、尿蛋白等指标的变化情况。结果实验组期待治疗时间为(14.6±2.6)d,而对照组期待治疗时间为(20.3±5.4)d,P<0.05。实验组D-二聚体降低较对照组明显,P<0.05。两组在治疗前后收缩压、舒张压、尿蛋白比较,均有P<0.05,但实验组在治疗后改善的更明显。结论低分子肝素联合硫酸镁对重度子痫前期具有较好的效果,值得在临床上应用。
Objective To study the curative effect of the severe preeclampsia with low molecular heparin combined magnesium sulfate. Methods Forty six severe preeclampsia patients treated in our hospital from March 2011 to Febru- ary 2012 were chosen, randomly divided into experimental group and control group, each group had 23 cases, the ex- perimental group was treated with the low molecular heparin combined magnesium sulfate, and the control group was treated with magnesium sulfate, the treatment time, blood coagulation function change, blood pressure, urine protein and the change of the index of two groups patients were analyzed. Results The treatment time of the experimental group was ＇（14.6±2.6） d, and the control group was （20.3±5.4） d, P 〈 0.05. D-dimer in experimental group was signifi- cantly lower than control group, P 〈 0.05. The systolic pressure, diastolic pressure, urine protein of two groups before and after treatment, all had P 〈 0.05, but the experimental group after treatment had more obvious improvement. Conclusion Low molecular heparin combined magnesium sulfate has good effect on severe preeclampsia, it is worth to clinical application.
出处
《中国当代医药》
2013年第11期168-169,共2页
China Modern Medicine
关键词
低分子肝素
硫酸镁
重度子痫前期
临床治疗
Low molecular heparin
Magnesium sulfate
Severe preeclampsia
Clinical treatment
