摘要
目的观察海昆肾喜胶囊联合丹参注射液治疗慢性肾衰竭的临床疗效。方法将60例慢性肾衰竭患者随机分为2组:观察组30例给予海昆肾喜胶囊联合丹参注射液治疗,对照组30例给予常规治疗,观察2组治疗效果、肾功能相关指标及生活质量改善情况。结果观察组总有效率明显高于对照组(P<0.05),血肌酐、血尿素氮、24 h尿蛋白水平明显低于对照组(P均<0.05),内生肌酐清除率明显高于对照组(P<0.05),KPS评分、QLQ-C30评分以及MUNSH评分均明显高于对照组(P均<0.05);2组不良反应无显著性差异。结论海昆肾喜胶囊联合丹参注射液治疗慢性肾衰竭疗效好,值得推广应用。
Objective It is to observe the clinical curative effects of Haikunshenxi capsule combined with Danshen injec- tion in on chronic renal failure （CRF）. Methods 150 cases of patients with CRF were randomly divided into 2 groups： obser- vation group（n = 30） was given Haikunshenxi capsule combined with Danshen injection and control group was given conven- tional therapy. Then the therapeutic effect, renal function indexes and quality of life were observed in both groups. Results The total effective rate of observation group was obviously higher than that of the control group （ P 〈 0.05）. The levels of ser- um creatinine, blood urea nitrogen and 24 h urine protein were significantly lower than those of the control group （ P 〈 O. 05 ） , endogenous creatinine clearance rate was obviously higher than that of the control group （ P 〈 0.05 ） , KPS scores, QLQ - c30 scores and MUNSH score were significantly higher than those of the control group （P 〈 0.05 ）. There was no significant difference in adverse reaction between both groups. Conclusion Haikunshenxi capsule combined with Danshen injection has a good curative efficiency on chronic renal failure, and this therapy is worth widely applieating in clinic.
出处
《现代中西医结合杂志》
CAS
2013年第13期1383-1384,1388,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
慢性肾衰竭
海昆肾喜胶囊
丹参注射液
肾功能
chronic renal failure
Haikunshenxi capsule
Danshen injection
renal function
