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CA125与TSGF联合检测在卵巢癌中的临床应用 被引量:16

Clinical application of combined detection of serum CA125 and TSGF in ovarian cancer
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摘要 为探讨CA125 、TSGF 联合测定在卵巢癌诊断、疗效观察中的价值,分别测定正常妇女、卵巢良性肿瘤患者和75 例卵巢癌患者术前和术后或治疗后的血清CA125 、TSGF 水平。结果:卵巢癌患者CA125 、TSCF 阳性率分别为88 .0 % 、90 .7 % ,联合测定阳性率为96 .0 % ;随访51 例术后患者中,有16 例患者血清CA125 和( 或) TSGF 升高,在血清学变化的3~12 个月内被临床证实转移或复发。认为联合测定CA125 、TSGF 不仅可提高卵巢癌的阳性诊断率,还可进行疗效观察及术后监测,且能达到早期诊断的目的。 In order to discuss the value of combined detection of CA125 and tumor specific growth factor (TSGF) in the diagnosis of ovarian cancer and the therapeutic effects, the serum level of CA125 and TSGF was detected, respectively in healthy women, patients with benign tumor of ovary and 75 cases of ovarian cancer before and after operation or after treatment. Results showed that positive rates of CA125 and TSGF in cases of ovarian cancer were 88% and 90.7%, respectively. The positive rate with combined detection was 96.0%. Serum CA125 and TSGF increased in 16 out of 51 follow-up cases. They were clinically confirmed to metastasize or recur within 3~12 months with serological changes. It could be concluded that the combined detection of CA125 and TSGF not only improves the diagnostic positive rate of ovarian cancer but also helps to observe therapeutic effect and postoperative monitoring and to reach the goal of early diagnosis.
作者 黄文成
出处 《右江民族医学院学报》 2000年第1期6-7,共2页 Journal of Youjiang Medical University for Nationalities
关键词 卵巢肿瘤 碳水化合物 抗原125 诊断 ovarian neoplasms carbohydrate antigen 125 malignant tumor specific growth
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参考文献2

  • 1连利娟.林巧雅妇科肿瘤学[M].北京:人民出版社,1994.458.
  • 2尹伯之.放射免疫分析在医学中的应用[M].北京:原子能出版社,1981.328.

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