摘要
目的 :观察肝病治疗仪及甘利欣注射液和中药联合治疗慢性乙型肝炎的疗效。方法 :治疗组 84例慢性乙型肝炎患者应用肝病治疗仪治疗 ,每日 1次 ,每次 30分钟 ;甘利欣注射液 15 0～ 2 0 0 mg加 10 %葡萄糖2 5 0 ml静滴 ;另用中药汤剂口服 ,每日 1剂 ;14日为 1个疗程 ,连用 2个疗程。对照组 84例采用西药治疗。观察临床症状、肝脾回缩情况、肝功能及 HBe Ag等指标。结果 :治疗组显效率为 73.8% ,总有效率为 10 0 .0 % ;对照组显效率为 44 .0 % ,总有效率为 79.8% ,2组比较均有显著性差异 (P均 <0 .0 1)。 HBe Ag阴转率治疗组为5 4.8% ,对照组为 2 2 .6 % ;治疗组治疗后血清中总胆红素〔(16 .12± 6 .41)μm ol/L〕、丙氨酸转氨酶〔(4 2 .10±13.91) U〕和对照组治疗后血清中总胆红素〔(30 .78± 10 .2 9)μm ol/L〕、丙氨酸转氨酶〔(79.18± 19.19) U〕均明显下降 (P均 <0 .0 5 )。结论 :肝病治疗仪及甘利欣注射液合中药联合治疗慢性乙型肝炎 ,在改善临床表现、肝功能和病毒学指标等方面疗效显著 。
Objective:To observe the curative effects of therapeutic instrument of hepatic disease combined with diammonium glyeyrrhizinate injection (DGI,甘利欣注射液) and Chinese herbs on chronic hepatitis B.Methods:Eightyfour cases with chronic hepatitis B in treatment group were treated with therapeutic instrument of hepatic disease for 30 minutes once a day,DGI +10% glucose 250 ml infused intravenously,and decoction of traditional Chinese medicine take orally once a day for 14 days as a therapeutic course.Two therapeutic courses were used continuously.Another 84 cases as control group were treated with western medicine alone.The following parameters,including clinical symptoms,shrink conditions of liver and spleen,hepatic functions,and HBeAg were observed.Results:The markedly effective rate was 73 8% and total effective rate was 100 0% in treatment group but they were 44 0% and 79 8% respectively in control group.In comparison between two groups the differences were significant (all P <0 01).The rate for HBeAg to transform into negative was 54 8% in treatment group but 22 6% in control group,so that the difference between two groups was significant ( P <0 05).After treatment the serum total bilirubin 〔(16 12±6 41)μmol/L〕 and alanine aminotransferase 〔ALT,(42 10±13 91)U〕 in treatment group and in control group 〔(30 78±10 29)μmol/L and (79 18±19 19)U〕 were significantly decreased (all P <0 05).Conclusions:The curative effects of therapeutic instrument of hepatic disease and DGI combined with Chinese herbs on chronic hepatitis B are obvious in aspects of improving clinical features,hepatic function,and transforming virologic parameters and sudiammonium glyeyrrhizinate injection;integrated traditional Chinese medicine and western medicine therapy
出处
《中国中西医结合急救杂志》
CAS
2000年第5期276-278,共3页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金
河南省平舆县科技攻关项目 !(No.930 0 6 )
