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芒柄花素衍生物的合成及其初步生物活性 被引量:10

Synthesis and Studies on the Preliminary Bioactivities of Derivatives of Formononetin
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摘要 设计合成了 8个芒柄花素 (7 羟基 4′ 甲氧基异黄酮 )衍生物 ,其中 7个为新化合物 ,并进行了体外初步抗骨质疏松活性实验 。 The synthesis of eight formononetin(7 hydroxy 4′ methoxyisoflavone) derivatives was reported in this paper and seven of them have never been reported in literature.Preliminary pharmacological tests of anti osteoporosis showed that all of the compounds could promote the growth of rabbits osteoblast in vitro .
出处 《中国药物化学杂志》 CAS CSCD 2000年第3期177-180,共4页 Chinese Journal of Medicinal Chemistry
关键词 芒柄花素 合成 抗骨质疏松 生物活性 formononetin synthesis anti osteoporosis
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参考文献3

  • 1Norman RF,Audrey SB,Geoffrey AC,et al.Potential value of plants as sources of new antifertility agents II[].Journal of Pharmacological Sciences.1975
  • 2Andrew P,Foot S.A new convenient synthesis of isoflavones[].Synthesis.1976
  • 3Anderson EL,Marrian GF.The identification of equol as 7-hydroxy-3-(4′-hydroxyphenyl) chroman and the synthesis of racemic equol methyl ether[].Journal of Biological Chemistry.1939

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