摘要
目的了解无锡地区颜面再发性皮炎患者的接触性变应原分布情况。方法对2008年6月-2012年3月本科门诊665例颜面再发性皮炎患者用"瑞敏"中国筛查系列变应原CH-1000斑贴试剂盒进行斑贴试验,结果进行统计学分析。结果斑贴试验阳性率83.01%,性别及年龄差异均无统计学意义(P均>0.05)。阳性率居前6位的变应原依次为重铬酸钾、氯化钴、硫酸镍、甲醛、卡巴混合物、对苯类(混合物)和芳香混合物。其中男性患者卡巴混合物、对苯类(混合物)、亚乙基二胺、巯基混合物和秋兰姆混合物的阳性率显著高于女性,女性患者硫酸镍阳性率显著高于男性;≥41岁的中老年组芳香混合物阳性率显著高于少儿组和青年组。以上差异均有统计学意义(P均<0.05)。结论重铬酸钾、氯化钴、硫酸镍、甲醛、卡巴混合物、对苯类(混合物)和芳香混合物是无锡地区颜面再发性皮炎的主要变应原。斑贴试验可明确患者接触性变应原的种类,对指导日常防护有重要意义。
Objective To analyze the contact allergens in patients with facial recun＇ent dermatitis （FRD） in Wuxi re-gion. Methods Six hundred and sixty-five patients with FRD underwent patch-test with the kit of Ruimin China （CH-1000） from June of 2008 to March of 2012 and the results were treated with statistic method. Results The percentage of positive patch test was 83.01% and there was no statistical significance between gender and age（all P 〉0.05）. Potassium dichromate, cobalt chloride, nickle sulfate, formaldehyde, carba mix, parabens and fragrance mix were the most frequent six allergens in these patients, among which carba mix, parabens, ethylenediamine dihydrochloride, sulfhydryl mix and thiuram mix were prone to be detected in males compared with females. However nickle sulfate was prone to be detected in females compared with males, The positive rate of fragrance mix of the middle-aged and elderly patients was significantly higher than that of the children and young patients. There were significant differences between them （ all P 〈 0.05 ）. Conclusion Potassium dichromate, cobalt chloride, nickle sulfate, formaldehyde, carba mix,parabens and fragrance mix are the main allergens of FRD in Wuxi region. Patch test can identify the variety of contact al-lergens and it is meaningful for the daily protection of patients with FRD.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2013年第5期472-474,共3页
The Chinese Journal of Dermatovenereology
