摘要
目的 探讨母亲梅毒治疗情况对新生儿先天性梅毒发病的影响。方法 新生儿先天性梅毒40例,按母亲治疗方法不同分为母亲正规治疗组20例、母亲非正规治疗组10例、母亲未治疗组10例。对各组新生儿先天性梅毒发病情况进行比较。结果 新生儿先天性梅毒可累及多个系统,表现为皮肤损害、病理性黄疸、肝脾肿大、水肿、贫血、血小板减少、骨损害、脑脊液异常等;母亲正规治疗组新生儿先天性梅毒发生率10%,明显低于非正规治疗的40%及未治疗组的50%（χ^2=11.2,P＜0.05;χ^2=20.4,P＜0.01）,非正规治疗组与未治疗组比较,新生儿先天性梅毒发生率差异无统计学意义（χ^2=0.68,P＞0.05）;该组治愈30例（75%）,好转7例（17%）,死亡3例（7%）。结论 积极防治母亲梅毒感染是预防新生儿先天性梅毒的关键。
Objective To explore the influence of mother′s treatment for syphilis on the incidence of congenital syphilis in newborn babies.Methods 40 cases of neonatal congenital syphilis,according to mother different treatment methods,were divided into regular treatment group（20 cases）,mother without regular treatment group（10 cases）,mother with no treatment group （10 cases）.The incidence of neonatal congenital syphilis was compare.Results The neonatal congenital syphilis could affect multiple systems,manifested as skin damage,pathological jaundice,hepatosplenomegaly,edema,anemia,thrombocy to penia,bone injury,cerebrospinal fluid abnormalities et al.The incidence rate of neonatal congenital syphilis in regular treatment group was 10%,which was significantly lower than normal treatment 40% and untreatment 50% （χ^2=11.2,P〈0.05;χ^2=20.4,P〈0.01）.The neonatal congenital syphilis incidence rate was not statistically significant between the informal group and untreatment group （χ^2=0.68,P〉0.05）;30 cases were cured（75%）,improved in 7 cases（17%）;3 cases died （7%）.Conclusion The prevention and treatment of syphilis infection in mothers are the key point to prevent neonatal congenital syphilis.
出处
《中国基层医药》
CAS
2013年第10期1519-1520,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
梅毒
先天性
婴儿
新生
Syphilis, congenital
Infant, newborn
