摘要
目的观察加减羚角钩藤汤联合西药治疗子痫前期的疗效及对妊娠结局的影响。方法将50例子痫前期患者随机分成西药组24例和联合组26例,西药组给予安定片及硫酸镁注射液治疗,联合组在西药组基础上加用羚角钩藤汤,两组均用药至孕妇分娩或终止妊娠,观察两组新生儿体重、新生儿Apgar评分、延长孕周时间、产后出血量、提前终止妊娠情况及重度患者孕周<34周情况。结果联合组新生儿出生体重较西药组重(P<0.01),孕周明显延长(P<0.01),计划外终止妊娠例数以及重度患者孕周<34周者均较西药组少(P<0.05)。两组患者产后出血量及新生儿Apgar评分比较差异无统计学意义(P>0.05)。结论加减羚角钩藤汤联合西药对子痫前期患者可延长孕周、改善妊娠结局。
Objective To observe the therapeutic effect of modified Lingjiao Gouteng Decoction [decoction of Lingjiao （Cornu Saigae Tataricae） and Gouteng （Ramulus Uncariae Cum Uncis）] combined with western medicine on preeclampsia and its impact on the pregnancy outcome. Methods Fifty cases of preeclampsia were randomized into the western medicine group of 24 cases and combo therapy group of 26 cases. The western medicine group was given conventional therapy including diazepare tablet and magnesium sulfate injection, and the combo therapy group was added with Lingjiao Gouteng Decoction. Both groups were treated before childbirth or termination of pregnancy. The birth weight, neonatal Apgar score, extend gestational weelfs, postpartum hemorrhage, early termination of pregnancy and severe patients less than 34-week gestation were observed in both groups. Results Comparing with the western medicine group, the birth weight was significantly heavier and the preg- nancy was significantly longer （P〈0.01）, while the numbers of unplanned termination of pregnancy and severe patients less than 34-week gestation were significantly smaller in the combo therapy group after termination of pregnancy （P〈0.05）. There was no significant difference between groups in the neonatal Apgar score and postpartum hemorrhage after delivery （P〉0.05）. Conclusion The combo therapy of modified Lingjiao Gouteng Decoction and western medicine for preeciampsia can extend gestational weeks and improve pregnancy outcome.
出处
《中医杂志》
CSCD
北大核心
2013年第10期855-857,共3页
Journal of Traditional Chinese Medicine
关键词
加减羚角钩藤汤
妊娠期高血压疾病
子痫前期
妊娠结局
Lingjiao Gouteng Decoction
hypertensive disorders in pregnancy
preeclampsia
pregnancy outcome
