摘要
目的:探讨阿昔洛韦致过敏性休克的特点和规律,为临床合理用药提供参考。方法:检索中国期刊全文数据库1994-2012年有关阿昔洛韦致过敏性休克的文献,结合临床发现的1例患者进行归纳和分析。结果:发生过敏性休克的5例患者中,3例为60岁以上老人;3例为静脉滴注给药,1例在外搽软膏的同时静脉滴注给药,1例为口服给药;静脉滴注2例在10min以内发生不良反应,1例在10min后发生,口服在用药1h后发生;4例为首次用药,1例为再次用药。结论:临床应重视阿昔洛韦致过敏性休克,加强20min内的用药监测,以确保用药安全。
OBJECTIVE：To explore the characteristics and regulation of anaphylactic shock induced by acyclovir,and to provide reference for rational drug use in the clinic.METHODS：Literatures about anaphylactic shock induced by acyclovir were retrieved from CNKI from 1994-2012 and analyzed statistically on the basis of a patient in the clinic.RESULTS：Among 5 cases of anaphylactic shock,3 cases were elderly people over the age of 60;3 cases were administered intravenously,1 case received both ointment for external use and intravenous administration,and 1 cases oral administration;2 cases of intravenous administration suffered from anaphylactic shock within 10 min,1 case after 10 min and oral administration after 1 h;4 cases were the first time medication,and 1 case was re-medication.CONCLUSIONS：Great importance should be attached to anaphylactic shock caused by acyclovir,and monitoring within 20 minutes after injection should be enhanced to ensure the security of drug use.
出处
《中国药房》
CAS
CSCD
2013年第20期1896-1898,共3页
China Pharmacy
关键词
阿昔洛韦
过敏性休克
文献分析
Acyclovir
Anaphylactic shock
Literature analysis
