摘要
目的:研究血清降钙素原(PCT)指导呼吸机相关性肺炎抗菌药物应用的价值。方法:选择37例呼吸机相关性肺炎(VAP)患者,随机分为常规组(n=17)和PCT组(n=20),常规组根据患者的一般临床资料指导抗菌药物应用,PCT组根据患者的一般临床资料及血清PCT水平指导抗菌药物应用。结果:PCT组与常规组VAP疗效无差异(P>0.05),但PCT组抗菌药物应用时间较常规组缩短(2.7±0.9天)(P<0.01)。结论:血清PCT水平指导下可以缩短VAP的抗菌药物疗程。
Objective：To study the significance of serum procalcitonin（PCT） directing antibiotic therapy in ventilator associated pneumonia.Methods：37 ventilator associated pneumonia（VAP） patients were randomly assigned to conventional group（n=17） and PCT group（n=20）.In conventional group the antibiotic therapy based on general clinical data of Patients.In PCT group the antibiotic therapy based on both of general clinical data and PCT of Patients.Results：The efficacy of antibiotic therapy had no difference in both group（P〉0.05）.Compared with conventional group,the course of antibiotic therapy shorten （2.7±0.9）days in PCT group（P〈0.01）. Conclusion：Serum PCT level directing antibiotic therapy in VAP can shorten the course of treatment.
出处
《中国医药导刊》
2013年第4期662-663,共2页
Chinese Journal of Medicinal Guide
关键词
降钙素原
呼吸机相关性肺炎
抗生素
Procalcitonin PCT Ventilator associated pneumonia VAP Antibiotic
