摘要
目的 评价金属支架治疗肺癌、食管癌等恶性肿瘤引起的气管狭窄的可行性和疗效。方法 30例肺癌、食管癌等恶性肿瘤压迫或侵犯气管 ,引起气管狭窄和严重的呼吸困难 ,分别置入自扩型金属支架。 11例患者进行了后续的化学治疗和放射治疗。结果 30例狭窄都位于主气管 ,共置入支架 30个 (12个GianturcoZ形支架 ,8个Wallstent支架 ,10个Ultraflex支架 )。所有患者呼吸困难得到立即缓解。 1例术后 6d死亡。 2例术后 10d失随访。 16例未行后续治疗的患者生存时间为 35～80d ,平均 6 5d。 7例进行化学治疗的患者生存时间为 40～ 95d ,平均 80d。 4例行放射治疗结合化学治疗患者生存时间 90d至 2年 ,平均 11个月。结论 气管支架能缓解晚期恶性肿瘤引起的呼吸困难 ,改善生活质量。
Objective To access the feasibility and efficacy of metallic stent in the treatment of malignant airway obstruction. Methods Thirty patients with lung cancer and esophageal cancer underwent placement of expendable metallic stents for respiratory distress caused by airway obstruction. 11 patients underwent additional therapy. Results All 30 stenosis were located in the trachea. Only one stent was placed in each stricture site (12 Gianturco Z stents, 8 Wallstents, 10 Ultraflex). One patient died six days after stenting. And 2 patients were lost 10 days later. 16 patients without additional therapy lived from 35 to 80 days (mean survival, 65 days) after stent placement. 7 patients with additional chemotherapy lived from 40 to 95 days (mean survival, 80 days) after stent placement. 4 patients with additional radiotherapy and chemotherapy had the mean survival period after stenting of 11 months (range, 90 to 730 days). Conclusion Although metallic stents are useful for relieving respiratory distress and improving life quality in patients with malignant airway obstruction, additional radiotherapy and chemotherapy should be considered.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2000年第10期680-684,共5页
Chinese Journal of Radiology
