期刊文献+

健康供者外周血造血干细胞动员及采集效果分析 被引量:10

下载PDF
导出
摘要 目的:研究影响外周血造血干细胞动员及采集的因素。方法:40例健康供者经单一粒细胞集落刺激因子动员后,经COM.TEC血细胞分离机采集外周血造血干细胞,分析不同健康供者的年龄、性别、分离前白细胞的数量、不同的动员方案对外周血造血干细胞采集的影响。结果:40例供者均成功采集:PBMNC(9.77±2.74)×108/kg、CD34+(5.07±6.5)×106/kg。分离前白细胞计数与PBMNC、CD34+呈正相关,年龄、性别、不同的动员方案未见统计学差异。结论:所有供者经合理动员后均可成功采集。
出处 《实用医学杂志》 CAS 北大核心 2013年第9期1463-1465,共3页 The Journal of Practical Medicine
  • 相关文献

参考文献10

  • 1De1 Fante C, Perotti C, Viarengo G, et al. Clinical impact of a new automated system employed for peripheral blood stem cell collection [ J ]. J Clin Apher, 2006,21 (4) : 227-232.
  • 2李春富,鲁灵龙,刘璇,李娜,吴学东.造血干细胞移植治疗阵发性睡眠性血红蛋白尿合并地中海贫血全球首例报告[J].南方医科大学学报,2012,32(3):425-426. 被引量:1
  • 3Yu J, Leisenring W, Bensinger W I, et al. The predictive value of white cell or CD34^+ cell count in the peripheral blood for timing apheresis and maximizing yield [J ]. Transfusion, 1999, 39(5) :442-450.
  • 4Shimizu N, Asai T, Hashimoto S, et al. Mobilization factors of peripheral blood stem cells in healthy donors [J]. Ther Apher, 2002,6(6) :413-418.
  • 5Sourgens H, Lefrere F. A systematic review of available clinical evidence-filgrastim compared with lenograstim [J]. Int J Clin Pharmacol Ther, 2011,49(8) :510-518.
  • 6Hadji P, Kostev K, Schroder-Bernhardi D, et al. Cost comparison of outpatient treatment with granulocyte colony- stimulatin factors (G-CSF) in Germany [J]. Int J Clin Pharmacol Ther, 2012,50(4) : 281-289.
  • 7de la Rubia J, Arbona C, de Arriba F, et al. Analysis of factors associated with low peripheral blood progenitor cell collection in normal donors [ J]. Transfusion, 2002,42( 1 ) : 4-9.
  • 8Ikeda K, Kozuka T, Harada M. Factors for PBPC collection efficiency and collection predictors [J]. Transfus Apher Sci,2004,31 (3) : 245-259.
  • 9Wuchter P, Ran D, Bruckner T, et al. Poor mobilization hematopoietic stem cells-definitions, incidence, risk factors and impact on outcome of autologous transplantation [J] Biol Blood Marrow Transplant, 2010, 16 (4) : 490-499.
  • 10张曦,李忠俊,陈幸华,张诚,高蕾,高力,龚奕,孔佩艳,刘红,彭贤贵.血液病患者/健康供者外周血造血干细胞动员及采集效果分析[J].中国输血杂志,2010,23(12):1010-1013. 被引量:13

二级参考文献16

  • 1Bosi A, Bartolozzi B, Guidi S. Allogeneic stem cell transplantation. Transplant Proceedings,2005,37 (6) :2667-2671.
  • 2Ikeda K, Kozuka T, Harada M. Factors for PBPC collection effi- ciency and collection predictors. Transfus Apher Sci ,2004,31 (3) : 245 -250.
  • 3Gaia S,Smedile A ,Omede P,et al. Feasibility and safety of G-CSF administration to induce bone marrow-derlved cells mobilization in patients with end stage liver disease. J Hepatol,2006,45 ( 1 ) :13- 19.
  • 4Carreras E. Risk assessment in haematopoietie stem cell transplan- tation:The liver as a risk factor. Best Practice Res Clin Haematol, 2007,20(2) :231-239.
  • 5Bhatia M, Davenport V, Cairo MS. The role of interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with solid tumors,lymphoma,acute myeloid leukemia and bone marrow failure syndromes. Leuk Lymphoma,2007,48( 1 ) :9-15.
  • 6Jacoub JF, Suryadevara U, Vivian P, et al. Mobilization strategies for the collection of peripheral blood progenitor ceils : Results from a pilot study of delayed addition G-CSF following chemotherapy and review of the literature. Exp Hematol,2006, 54 ( 11 ) : 1443- 14-50.
  • 7Cheerva AC, Breslin N, Monica H, et al. Pediatric patients demon- strate low absolute peripheral blood CD34^+ cells for adequate stem cell collection. Biol Blood Marrow Transplant,2006,12 (2) : 105- 111.
  • 8Lysak D, Koza V ,Jindra P. Factors affecting PBSC mobilization and collection in healthy donors. Transfus Apher Sci, 2005,33 ( 3 ) : 275-281.
  • 9Xinghua Chen,Lei Gao,Xi Zhang,et al. HEA-haploidentical blood and marrow transplantation with anti-thymocyteglobulin:long-term comparison with HLA-identical sibling transplantation. Blood ceils, Mol Dis,2009,43:98-104.
  • 10Achievements RC,limitations of complement inhibition byeculizumab in paroxysmal nocturnal hemoglobinuria:the role ofcomplement component 3[J].Mini Rev Med Chem,2011,11(6):528-35.

共引文献12

同被引文献53

引证文献10

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部