摘要
目的:探讨肝硬化食管静脉曲张套扎术后再出血的影响因素,为套扎术后再出血的预防提供科学依据。方法:采用整群抽样获取研究对象,采用病例对照研究对套扎术后再出血的影响因素进行非条件Logistic多元逐步回归分析。结果:肝硬化食管静脉曲张内镜下套扎治疗术后二次出血的发生率为11.25%,性别(OR=0.163)是套扎术后再出血的保护因素,进食硬质食物(OR=23.696)、肝功能Child-pugh分级高(OR=5.703)、食管曲张静脉数量多(OR=30.637)和食管静脉曲张Grade分级高(OR=6.143)是其危险因素。结论:肝硬化食管静脉曲张内镜下套扎术后二次出血的发生率较高,应加强对男性患者的教育,术后早期应避免进食硬质食物,并且严格掌握套扎术的手术适应症和禁忌症是减少套扎术后再出血的重要途径。
Objective： To investigate the influencing factors ofrebleeding after esophageal variceal ligation（EVL）, and provide the evidences for prevention of it. Methods： A case-control study was conducted. The EVL patients were collected from January 2007 to November 2011 in Weinan Center Hospital by cluster sampling consecutively. The data were analyzed by mono-factorial and multi-factorial non-conditional logistic regression by SPSS 13.0 software. Results： The incidence rate of early rebleeding after EVL was 11.25%. The significant findings were obtained that the female is more fortunate than male（OR=0.163）, eating hard food（OR=23.696）, B or C class of liver function Child-pugh classification（OR=5.703）, more amount esophago varicose vein（OR=30.637） and severe class of esophago varicose vein Grade classification （OR=6.143） were the risk factors of early rebleeding after esophageal variceal ligation. Conclusion： The incidence rate ofrebleeding after EVL was still high, doctors should strengthen the education time for male patients, and avoid eating hard food of early rebleeding after esophageal variceal ligation. Moreover, strict control of the surgical indications and contraindication were important to reduce the incidence rate of rebleeding.
出处
《现代生物医学进展》
CAS
2013年第12期2318-2320,共3页
Progress in Modern Biomedicine
关键词
食管静脉曲张
套扎术
再出血
影响因素
Esophageal varices
Endoscopic variceal ligation（EVL）
Rebleeding
Influential factors
