摘要
目的:分析辛伐他汀治疗短暂性脑缺血发作(TIA)的临床效果,为TIA的二级预防提供参考。方法:将92例TIA患者随机分为两组,A组45例给予阿司匹林肠溶片治疗,B组47例给予辛伐他汀治疗,观察两组治疗效果。结果:B组治疗总好转率为89.36%,高于A组的73.33%(P<0.05);治疗后B组TC、TG、LDL水平低于A组(P<0.05);B组HDL水平高于A组(P<0.05);B组脑梗死发生率、TIA复发率分别为6.38%、10.64%,均低于A组的22.22%、28.89%(P<0.05)。结论:辛伐他汀治疗短暂性脑缺血发作疗效显著,可显著改善血脂水平,脑梗死发生率及复发率低,预后良好。
Objective： To analyze the effects of Simvastatin on transient ischemic attack.Methods： A total of 92 patients with TIA were randomly divided into two groups,group A（45 patients） were given enteric-coated aspirin tablets,group B（47 patients） were treated with simvastatin.Therapeutic effects of the both groups were observed.Results：89.36% patients of group A showed improvement,higher than the 73.33% of group B（P0.05）.After treatment,TC,TG,LDL level of group B was lower than that in group A,but HDL level was higher（P both0.05）.In group B,the rate of cerebral infarction,and TIA recurrence rate were 6.38% and 10.64%,respectively,both were lower 22.22% and 28.89% of group A（P0.05）.Conclusion： Simvastatin shows great effects on transient ischemic attack,it can significantly decrease lipid levels to reduce cerebral infarction incidence and recurrence rate,which is good for patients＇ prognosis.
出处
《海南医学院学报》
CAS
2013年第6期760-762,共3页
Journal of Hainan Medical University
基金
中国高校医学期刊临床专项资金项目(112210661)~~
关键词
短暂性脑缺血发作
辛伐他汀
脑梗死
治疗
Transient ischemic attack
Simvastatin
Cerebral infarction
Treatment
