摘要
目的研究沙门菌感染的血清型分布特点及耐药情况,为临床合理用药提供参考。方法对收集到的163例临床标本进行沙门菌分离培养、血清分型鉴定和药敏试验。结果 163株沙门菌中甲型副伤寒沙门菌80株(49.1%),伤寒沙门菌17株(10.4%),鼠伤寒沙门菌40株(24.5%),肠炎沙门菌19株(10.4%),猪霍乱沙门菌4株(2.4%);甲型副伤寒沙门菌、伤寒沙门菌、鼠伤寒沙门菌、肠炎沙门菌以环丙沙星、左氧氟沙星、头孢噻肟、头孢曲松、亚胺培南比较敏感,氨苄西林、复方磺胺甲噁唑、链霉素、氯霉素的耐药现象比较严重。结论临床应根据药敏试验合理使用抗生素,尽量减少耐药菌株的产生。
Objective To study the characteristics of the serotype distribution of Salmonella infection and drug resistance in the region, and provide reference for clinical rational drug use. Methods 163 cases of clinical specimens were isolated and cultured, and identified Salmonella serotype, drug sensitivity was measured. Results 163 strains of Salmonella included 80 strains of Salmonella paratyphi（49.1%）, 17strains of Salmonella typhi（10.4%）, 40 strains of Salmonella typhimurium（24.5%）, 19 strains of Salmonella enteritidis（10. 4%）and 4 strains of Salmonella choleraesuis （2. 4%）. Salmonella paratyphi A, Salmonella, Salmonella typhimurium and Salmonella enteritidis were seriously resistanta to ciprofloxacin, levofloxacin, eeftriaxone, eefotaxime, imipenem sensitive,, ampicillin, compound sulfamethoxazole, streptomycin and ehloramphenicol. Conclusion Clinical use of antibiotics should be based on the drug sensitive test, minimize the emergence of drug-resistant strains.
出处
《西部医学》
2013年第2期286-287,共2页
Medical Journal of West China
基金
江西省卫生厅课题(20100467)
关键词
沙门菌
血清型
药敏分析
耐药
Salmonella serotypes
Analysis
Drug resistance
