摘要
目的研究对妊娠期梅毒患者母婴传播的阻断方法及效果。方法回顾性分析2009年1月至2012年1月间入院治疗并全程随访的217例妊娠期梅毒患者,其中33例患者未经过任何阻断治疗作为对照组,184名患者经过注射用青霉素钠及苄星青霉素治疗作为实验组。定期检查两组患者梅毒螺旋体明胶颗粒凝集试验(TPPA)及快速血浆反应素试验(RPR)结果。观察两组患者终止妊娠、死胎、足月梅毒儿、足月健康儿等生产情况。结果实验组足月产181例(98.37%),早产3例(1.63%),死胎0例;对照组足月产28例(84.85%),早产3例(9.09%),死胎2例(6.06%)。实验组正常新生儿175例(95.11%),先天梅毒儿9例(4.89%);对照组分别为24例(72.73%)和9例(27.27%)。结论对妊娠梅毒患者实行母婴梅毒阻断具有良好的效果,可为临床提供良好的参考。
Objective To study the method and effect of blocking maternal-fetal transmission of syphilis during pregnancy. Methods 217 cases of pregnant women with syphilis who hospitalized from January 2009 to January 2012 were analyzed retrospectively. Among them, 33 patients without any blocking treatment were divided into the control group, 184 patients with penicillin sodium and benzathine penicillin treatment were divided into the experimental group. Results of treponema pallidum particle agglutination tests （TPPA） and rapid plasma reagin tests （RPR） of the two groups were compared. The situation of terminate pregnancy, stillbirth, production of full-term syphilis children and full-term healthy children were observed. Results In the experimental group, 181 cases （98.37%） were full-term delivery, 3 cases （1.63%） were preterm delivery, no case was stillbirth. In the control group, the data were 28 cases （84.85%）, 3 cases （9.09%）, and 2 cases （6.06%） respectively. In the experimental group, normal newborns were 175 cases （95.11%）, congenital syphilis children were 9 cases （4.89%）, while those were 24 cases （72.73%） and 9 cases （27.27%） in the control group. Conclusions Blocking maternal-fetal transmission of syphilis during pregnancy is effective, and it can provide a good reference for the clinical practice.
出处
《临床医学工程》
2013年第5期563-564,共2页
Clinical Medicine & Engineering
关键词
妊娠梅毒
母婴传播
阻断
效果评价
Pregnancy syphilis
Maternal-fetal transmission
Blocking
Effect valuation
