摘要
目的:关于将骨化三醇用于治疗慢性肾功能衰竭肾性骨病患者所取得的疗效进行分析探讨。方法:选取在笔者所在医院接受治疗的66例慢性肾功能衰竭肾性骨病患者,将患者随机分成两组。对照组患者进行常规治疗。实验组患者在进行常规治疗的同时采用骨化三醇治疗。比较并观察两组患者治疗后各指标的变化情况,以及观察治疗后两组患者出现不良反应的情况。结果:两组患者进行不同方法治疗后,实验组血清钙(2.46±0.39)mmol/L明显高于对照组(1.99±0.37)mmol/L,比较差异有统计学意义(P<0.05)。实验组血磷、碱性磷酸酶、尿素氮、肌酐明显低于对照组,比较差异有统计学意义(P<0.05)。结论:采用骨化三醇用于治疗慢性肾功能衰竭肾性骨病比常规治疗的效果好,可以加快钙的吸收,降低患者体内血磷、碱性磷酸酶、尿素氮、肌酐水平,可有效改善肾性骨病,且不良反应发生率低,在临床上可以广泛运用。
Objective： To discuss and analyze curative effect of using calcitriol to treat chronic renal failure renal osteopathy patients.Method： Chose 66 cases of these chronic renal failure renal osteopathy patients who have been treated at our hospital, divided them into control group and experimental group randomly.Proceeded conventional treatment to control group＇s patients, while added calcitriol to experimental group＇s patients on the basis of conventional treatment.Compared and observed these two groups＇patients＇change situations of various indexes after treatment, and observed their happening con^titions of adverse reactions after treatment.Result： After these two groups patients received different treatments, experimental group＇s serum calcium content （ 2.46 ±0.39 ） mmol/L was obviously higher than control group＇ s （ 1.99± 0.37 ） retool/L, it has statistics meaning （ P〈0.05 ） . Experimental group＇s blood phosphorus, alkaline phosphatase, urea nitrogen and creatinine were evidently lower than control group＇s, it has statistics meaning （P〈0.05） .Conclusion： Calcitrlol＇s treatment effect on chronic renal failure renal osteopathy is better than conventional treatment＇s, it can speed up absorption of calcium, reduce patients＇ blood phosphorus, alkaline phosphatase, urea nitrogen and creatinine levels, improve treatment effect of renal osteopathy effectively, and its happening rate of adverse reactions is low, it is worthy of wide clinical promotion.
出处
《中国医学创新》
CAS
2013年第15期35-36,共2页
Medical Innovation of China
关键词
骨化三醇
慢性肾功能衰竭
肾性骨病
临床疗效
Calcitriol
Chronic renal failure
Renal osteopathy
Clinical curative effect
