摘要
对川山橙的化学成分进行研究,通过采用硅胶柱、ODS、Sephadex LH-20等柱色谱方法进行分离纯化,根据理化性质与波谱数据鉴定了14个化合物的结构,分别为11-hydroxytabersonine(1),venalstonidine(2),sandine(3),齐墩果酸(4),熊果酸(5),白桦脂醇(6),(+)松脂醇(7),(-)丁香脂素(8),8-羟基-松脂素(9),(-)-latifolin(10),甲基条叶蓟素(11),马钱素(12),对苯二甲酸二丁酯(13),β-谷甾醇(14),其中化合物4～14为首次从该植物中分离得到。
To study the chemical constituents in the twigs and leaves of Melodinus hemsleyanus. The chemical constituents were isolated by silica gel, ODS and Sephadex LH-20 column chromatographies. Their structures were determined by chemical and spectroscopic methods. Fourteen compounds were isolated from the 95% ethanol extract of the twigs and leaves of M. hemsleyanus. Their structures were identified as 11-hydroxytabersonine （ 1 ）, venalstonid （2）, sandine （3）, oleandic acid （4）, ursolic acid （5）, betulin （6）, （ ＋ ）-pinoresinol （7）, （ - ）-syringaresinol （8）, 8-hydroxypinoresinol （9）, （ - ）-latifolin （10）, eirsilineol （11）, loganin （12）, dibutylterephthalate （13）, and β-sitosterol （14）. Compounds 4-14 were obtained from this plant for the first time.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2013年第10期1548-1551,共4页
China Journal of Chinese Materia Medica
基金
教育部长江学者创新团队项目(IRT0965)
中央高校基本科研业务费专项(21612203)
关键词
川山橙
化学成分
生物碱
木脂素
Melodinus hemsleyanus
chemical constituents
alkaloid
lignans
