摘要
该实验针对石见穿醋酸乙酯部位化学成分进行研究。采用硅胶、ODS、Sephadex LH-20柱色谱和高效液相制备色谱进行分离纯化,运用NMR和MS等波谱学方法,并结合文献对照确定了化合物的结构。从石见穿醋酸乙酯部位中分离鉴定了11个化合物,分别为:oresbiusin A(1),ethyl dihydrocaffeate(2),迷迭香酸乙酯(3),迷迭香酸(4),迷迭香酸甲酯(5),bis(2-ethylhexyl)phthalate(6),丹酚酸C(7),丹酚酸C甲酯(8),丹酚酸A甲酯(9),紫草酸B二甲酯(10),丹酚酸A(11)。除迷迭香酸外,其他化合物均为首次从该植物中分离得到。
Chemical constituents were investigated on the ethyl acetate extract of Salvia chinensis. Compounds were separated and purified by various chromatograhic techniques including silica gel, Sephadex LH-20 and reversed-phase HPLC. Their structures were identified by spectroscopic data analysis. Eleven compounds were isolated and purified and their structures were identified as ores- biusin A（ 1 ）, ethyl dihydrocaffeate （ 2 ）, ethyl rosmarinate （ 3 ）, rosmarinic acid （ 4 ）, methyl rosmarinate （ 5 ）, bis （ 2-ethylhexyl ） phthalate （6）, salvianol acid C （ 7 ）, methyl salvianol acid C （ 8 ）, methyl salvianolate A （ 9 ）, dimethyl lithospermate B （ 10 ）, and salvianolic acid A（ll ）. Except for rosmarinic acid, the remaining compounds were isolated from S. chinensis for the first time.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2013年第10期1556-1559,共4页
China Journal of Chinese Materia Medica
基金
国家自然科学基金项目(81073060)
关键词
石见穿
唇形科
化学成分
Salvia chinensis
Labiatae
chemical constituents
