摘要
以DL-丝氨酸为原料,先采用氨基酸关环法化学合成酶的作用底物———DL-5-羟甲基海因,收率93.5%。然后,该底物在酶的作用下,起始pH=9.0,培养温度38℃,转化时间42 h,经过一系列的酶解反应即得到D-丝氨酸,收率为81.7%。
The substrate DL-5-hydroxymethylhydantoin was synthesized from DL-serine through a chemical process of amino acid cyclization method with a yield of 93.5%. And then D-serine was produced by the biotransformation of DL-5-hydroxymethylhydantoin under the conditions of pH 9.0, temperature of 38 ℃ and conversion time of 42 hours with a yield of 81.7%.
出处
《精细化工》
EI
CAS
CSCD
北大核心
2013年第5期510-512,共3页
Fine Chemicals
