摘要
目的观察度洛西汀对老年骨性膝关节炎的临床治疗效果。方法选取2011年1月～2012年6月间进行门诊治疗的老年骨性膝关节炎患者120例,给予度洛西汀治疗,观察记录治疗前后患者关节疼痛情况、关节僵硬程度、关节活动障碍、生活质量、运用WOMAC骨性关节炎指数评分表评分,综合评价治疗效果。结果临床痊愈8例,显效49例,有效54例,无效9例,总有效率为92.5%。治疗过程中没有发生严重不良反应,均能耐受。结论度洛西汀对老年骨性膝关节炎具有较好的临床治疗效果和推广应用前景,对于其不良反应要密切关注,加强研究。
Objective To observe the clinical effect of duloxetine on elderly patients with knee joint osteoarthri- tis. Methods 120 cases of elderly patients with knee joint osteoarthritis, who were given ambulatory treatment in our hospital from January,2011 to J une,2012,were chosen to be treated with duloxetine. The WOMAC form was used to score the joint pain,joint stiffness, the degree of joint movement disorder and life quality of the patients. And the ther- apeutic effect was synthetically scored as well. Results Among the patients,8 cases were cured, 49 showed signifi- cant effect,54 got effect,and 9 failed the therapy. The overall effective rate reached to 92.5%. No serious adverse re- actions were found in the process of treatment, which all the patients could endure. Conclusion Duloxetine has good clinical effect and positive prospects of applying to treating elderly patients with knee joint osteoarthritis. But its ad- verse reactions should be noted intensely and further studied.
出处
《右江医学》
2013年第2期171-172,共2页
Chinese Youjiang Medical Journal
基金
广东省科技计划项目(粤科规划字[2012]201号)
