摘要
目的:建立银青口溃含片薄层色谱鉴别和含量测定方法。方法:采用TLC法对方中青黛、冰片两味药进行定性鉴别;采用HPLC法对方中金银花的有效成分绿原酸进行含量测定。结果:本品定性鉴别薄层色谱特征明显,专属性强;方法学考察表明,绿原酸进样量在0.043 2～0.432 0μg范围内具有良好的线性关系(r=0.999 9),平均回收率为100.2%(RSD=1.28%,n=6)。结论:该法简便、准确、重复性好,可用于银青口溃含片的质量控制。
Objective：To establish a TLC identification method and a determination method of Yinqing oral ulcer buccal tablets. Method：Qingdai and borneol were identified by TLC.The content of chlorogenic acid in honeysuckle was determined by HPLC.Result： The characteristics of chlorogenic acid in TLC were distinct and highly specific.A good linear correlation for the chlorogenic acid was found within the range of 0.043 2-0.432 0μg（r = 0.999 9 ）.The average recovery of chlorogenic acid was 100.2%（RSD = 1.28%,n =6）.Conclusion：The method is simple,accurate and reproducible,and can be used in the quality control of Yinqing oral ulcer buccal tablets.
出处
《中国药师》
CAS
2013年第5期672-674,共3页
China Pharmacist
