摘要
直肠癌是常见的恶性肿瘤,随着生活水平提高及饮食习惯原因的改变,直肠癌发病率呈上升趋势。外科手术切除仍是直肠癌最主要的治疗手段,但局部晚期直肠癌患者术后局部复发率高,保肛率低,治疗效果不尽人意。近年,直肠癌新辅助放化疗逐渐受到广泛关注,本文从新辅助放化疗的优点及适应证、新辅助放化疗常用药物、新辅助放疗方案、新辅助放化疗疗效及新辅助治疗后的手术时机选择等方面进行综述。
Rectal cancer is a frequent malignant tumor,as the living standards ′ improving and the reasons for the changes in people＇s diet,the colorectal cancer incidence is on the rise.Surgical resection is still the most main treat ment for colorectal cancer,but the treatment effect is unsatisfactory in patients with postoperatively locally advanced rectal cancer because of the high local recurrence rate and low anal preservation rate.In recent years,neoadjuvant therapy for colorectal cancer has gained increasingly interest,this essay summarizes neoadjuvant chemoradiation ad vantages and indications,commonly used drugs for neoadjuvant chemoradiation,neoadjuvant radiotherapy plan,neoad juvant chemoradiation curative effect and timing of surgery after neoadjuvant therapy.
出处
《中国医药导报》
CAS
2013年第15期40-42,共3页
China Medical Herald
关键词
直肠癌
新辅助放化疗
进展
Rectal cancer
Neoadjuvant chemoradiation
Advance
