摘要
目的观察早期高压氧治疗急性颈髓损伤患者运动功能和神经功能恢复的效果，并探讨其作用机制。方法经患者知情同意并签署知情同意书后，将30例急性颈髓损伤患者按数字表法随机分成A组和B组。A组仅给予常规的急性颈髓损伤治疗，B组在常规治疗基础上于伤后48h内开始应用高压氧治疗。确诊后和治疗过程中应用美国脊髓损伤协会（American Spinal Injury Association,ASIA）评分标准对2组患者进行神经感觉和运动功能评分，并对治疗前和治疗2周后的评分进行统计学分析。结果治疗前，2组神经功能评分差异无统计学意义（P〉0．05）；治疗2周后，B组运动功能评分与神经功能评分（74．40±16．83，151．60±36．86）明显优于A组（60．13±16．44，120．40±34．68），差异均有统计学意义（P〈0．05）。结论早期应用高压氧治疗对急性颈髓损伤患者运动功能和神经功能的恢复有明显促进作用。
Objective To observe the effect of early hyperbaric oxygen therapy on the recovery of neurological function in patients with acute cervical spinal cord injury. Methods With the knowledge and consent of the patients and following the signing of the letter of agreement, 30 patients with acute cervical spinal cord injury were randomly assigned to 2 groups： group A and group B. Patients in group A were only given routine treatment for acute cervical spinal cord injury, while patients in group B were given HBO therapy 48 hours after injury, in addition to routine treatment. Following diagnosis of the injury and also in the course of treatment, the American Spinal Injury Association （ASIA） classification scale was used to measure the scores of neurosensory and motor functions of the patients in group A and group B. Then, statistical analysis was made on the scores of the patients in both groups, both before treatment and 2 weeks after treatment. Results Before treatment, there was no statistical significance in the neurological scores of group A and group B （ P 〉 0. 05 ）. After 2 weeks of treatment, statistical differences could be noted in the neurological scores of the 2 groups （ P 〈 0.05）, with the neurological scores of group B being obviously superior to those of group A （ P 〈 0.05 ）. Conclusions Early HBO therapy could obviously promote the recovery of neurological and motor functions, following acute cervical spinal cord injury.
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
北大核心
2013年第2期73-75,85,共4页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
关键词
急性颈髓损伤
神经功能
运动功能
高压氧
Acute cervical spinal cord injury
Neurological function
motor function
Hyperbaric oxygen
