期刊文献+

降钙素原在儿科感染性疾病中的临床价值 被引量:14

下载PDF
导出
摘要 感染性疾病目前仍是儿科常见疾病,广泛存于儿科领域的各个专业,除常见的肺炎和腹泻外,心血管系统、中枢神经系统、血液系统、泌尿生殖系统都常有感染存在。血清降钙素原(procalcitonin,PCT)作为一种具有高度灵敏性、特异性的实验室指标,可以早期鉴别细菌与非细菌感染,预警全身严重感染,指导临床合理使用抗生素以及评价治疗效果、判断疾病预后。近年来,越来越多的研究资料均显示出PCT在临床的应用价值优于血白细胞计数、CRP等指标,现就PCT的研究进展及临床应用价值做一综述如下。
出处 《中华全科医学》 2013年第7期1106-1106,1114,共2页 Chinese Journal of General Practice
  • 相关文献

参考文献22

  • 1Fioretto JR, Borin FC, Bonatto RC, et al. Procalcitonin in children with sepsis and septic shock [ J ]. J Pediatr,2007,83 (4) : 323.
  • 2Stolz D,Christ-Crain M, Bingisser R, et al. Antibiotic treatment of ex- acerbations of COPD : a randomized controlled trial comparing proealci- tonin guidance with standard therapy [ J ]. Chest, 2007,131 ( 1 ) :9 -19.
  • 3Purkayastha S, Chow A, Athanasian T, et al. Dose serum procalcitonin have a role in vealuating the severity of acute pancreatitis. A question revisited[J]. World J Surg,2006,30(9) :1713-1721.
  • 4Keshet R, Boursi B, Maoz R, et al. Diagnostic and prognostic signifi- cance of serum C-reactive protein levels in patients admitted to the de- partmentof medicine[J]. Am J Med Sci,2009,337(4) :248-255.
  • 5Lopez Sastre JB, Perez Solis D, Roques Serradilla V, et al. Procalcito- nin is not sufficiently reliable to be the sole marker of neonatal sepsis of nosocomial origin[ J]. BMC Pediatr,2006,6 : 16.
  • 6Guibourdenche J, Bedu A, Petzold L, et al. Biochemical markers of neonatal sepsis:volue of procalcitonin in the emergency setting[ J ]. Ann Clin Biochem,2002,39 ( 2 ) : 130-135.
  • 7Nobre V, Harbarth S, Graf JD, et al. Use of procalcitonin into shorten antibiotic treatment duration in septic patients:a randomized trial [ J ]. Am J Respir Crit Care Med,2008,177 (5) :498-505.
  • 8Christ-Crain M, Stolz D, Bingisser R, et al. Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia : a randomized tri- M [ J ]. Am J Respir Crit Care Med ,2006,174 (1) :84-93.
  • 9Alien L, Hsiao M, Douglas B. Fever in the new millennium : a review of recent studies of markers of serious bacterial infection in febrile chil-dren [ J ]. Curt Opin Pediatr,2005,17 ( 1 ) :56.
  • 10Koeabas E, Sarikeioglu A, Aksaray N, et al. Role of proealeitonin, C- reaction protein,interleukin-6 ,interleukin-8 and tumor necrosisfactor- alpha in the diagnosis of neonatal sepsis[ J ]. Turk J Pediatr,2007,49 (1) :7-20.

二级参考文献26

  • 1陈大庆.新生儿败血症辅助检查评价[J].实用儿科临床杂志,2005,20(2):102-105. 被引量:58
  • 2刘春峰,蔡栩栩,许巍.血降钙素原在儿童化脓性脑膜炎与病毒性脑膜炎中的变化[J].中国当代儿科杂志,2006,8(1):17-20. 被引量:38
  • 3Goldstein B,Giroir B,Randolph A.International ConsensusConference on Pediatric Sepsis:international pediatric sepsisconsensus conference:definitions for sepsis and organ dysfunc-tion in pediatrics.Pediatr Crit Care Med,2005,6(1):2-8.
  • 4Ng PC,Lam HS.Diagnostic markers for neonatal sepsis.CurrOpin Pediatr,2006,18(2):125-131.
  • 5Maruna P,Nedelnikova K,Gurlich R.Physiology and genet-ics of procalcitonin.Physiol Res,2000,49Suppl 1:57-61.
  • 6Carlet J.Rapid diagnostic methods in the detection of sepsis.Infect Dis Clin North Am,1999,13(2):483-494.
  • 7Christ-Crain M, Mttller B. Procalcitonin in bacterial infectious type, hope, more or less? [J] Swiss Med Wkly, 2005,135(31-32) : 451-460.
  • 8Nobre V, Harbarth S, Graf JD, et al. Use of procalciton in to shorten antibiotic treatment duration in septic patients: a randomized trial [J] . Am J Respir Crit Care Med, 2008, 177 (5) : 498-505.
  • 9Christ-Crain M,Stolz D, Binglsser R, et al. Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized tri- al[ J]. Am J Respir Crit Care Med,2006,174( 1 ) :84-93.
  • 10樊寻梅,周永涛.化脓性脑膜炎[M]//胡亚美,江载芳.诸福堂实用儿科学.7版.北京;人民卫生出版社,2002:912-926.

共引文献61

同被引文献159

引证文献14

二级引证文献117

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部