摘要
目的观察中药联合枸橼酸氯米芬胶囊治疗排卵障碍性不孕症的临床疗效。方法将100例排卵障碍性不孕症患者随机分为2组,治疗组60例应用中药联合枸橼酸氯米芬胶囊治疗,对照组40例单纯应用枸橼酸氯米芬胶囊治疗。2组均3个月经周期为1个疗程,治疗1个疗程后统计疗效,观察排卵及妊娠情况,阴道超声监测卵泡的发育、大小及子宫内膜厚度。结果治疗组妊娠率65.00%,对照组妊娠率32.50%,治疗组妊娠率高于对照组(P<0.05)。2组排卵期卵泡大小、子宫内膜厚皮均较本组治疗前增大(P<0.05),治疗组治疗后排卵期子宫内膜厚度高于对照组(P<0.05)。治疗组总有效率81.67%,对照组总有效率75.00%,2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。结论中药联合枸橼酸氯米芬胶囊治疗排卵障碍性不孕症,诱导排卵效果好,同时能提高子宫内膜的容受性,提高妊娠率,改善子宫内膜厚度。
Objective To investigate the effect of Chinese medicine combined with Clomifene citrate capsule on the treatment of ovulatory disorder infertility.Methods 100 cases of ovulatory disorder infertility were randomly divided into two groups,treatment group（n=60） received Chinese medicine combined with Clomifene citrate capsule and control group received Clomifene citrate capsule only.Three menstrual cycles was as a course of treatment in two groups.The effect was evaluated after a course of treatment.The changes of ovulation and pregnancy were observed.The development of follicles,size and endometrial thickness were monitored by vaginal ultrasound.Results Pregnancy rate in treatment group（65.00%） was higher than that in control group（32.50%,P〈0.05）.Follicle size and endometrial thickness after treatment was increased as compared with that before treatment in two groups ovulation period（P〈0.05）.There was not statistically significant between two groups on follicle development size ovulation period（P〈0.05）.Ovulation endometrial thickness in treatment group was higher than that in the control group（P〈0.05）.The total effective rate in treatment group（81.67%） was higher than that in control group（75.00%,P〈0.05）.Conclusion Chinese medicine combined with Clomifene citrate capsule can significantly increase ovulation,endometrial receptivity and pregnancy rate,and improve endometrial thickness,it is worthy of clinical application.
出处
《河北中医》
2013年第3期378-380,共3页
Hebei Journal of Traditional Chinese Medicine
关键词
不育
女(雌)性
中西医结合疗法
无排卵
Infertility
Female
Combined therapy of Chinese and Western medicine
Anovulation
