摘要
目的观察肝硬化门脉高压患者食管曲张静脉套扎 (EVL)术后门脉高压性胃病 (PHG)的发生及原PHG加重情况。方法由同一组医师对肝硬化食管静脉曲张病人进行胃镜检查 ,EVL术直至曲张静脉消失或明显减轻为止 ,定期胃镜检查 ,观察PHG的发生。结果58例病人术前发现PHG10例 (17.2 % ) ,2例合并消化道出血 ;58例89次EVL术后发生PHG17例 (29.3 % ) ,原有PHG加重3例 ,6例合并上消化道出血 ,两者比较均无统计学差异 (P>0.05) ;EVL术后有效40例发生PHG15例 (35.7 % ) ,无效18例发生PHG2例 (11.1 % ) ,两者比较有统计学差异 (P<0.05) ;EVL术后发生的PHG与套扎环数及时间呈明显正相关 ,r分别为0.932和0.994 ,平均发生时间为8.53个月。结论EVL术后曲张静脉消失或明显减轻的患者可发生PHG ,且随EVL术环数及时间的增加而增多。
Objective To observe the incidence or aggravation of portal hypertensive gastropathy (PHG) after endoscopic variceal ligation(EVL). Methods 89 sessions of EVL were practised on 58 patients with portal hypertension and followed up by periodic endoscopy. The procedures were performed by the same team of doctors. Results PHG was observed preoperatively in 10 cases (17.2%), including bleeding in 2, After EVL that was noted in 17 (21.3%) and aggravated in 3, including bleeding in 6, with no difference (P>0.05). PHG developed in 15 out of 40 (35.7%) cases with elimination of varices following EVL. However PHGwas discovered in only 2 out of 18 (11.1%) cases who had persistent varices after ligation. There was statistical difference (P<0.05). The onset of PHG related positively with the number of ring used for ligation and the time elapsed after EVL (r=0.932 and 0.994 respectively). The mean time of onset of PHG being 8.53 months. Conclusion PHG is likely to take place if the varices disappear or alleviate after ligation. Moreover the incidence of PHG rises with the increase in ring used and time of follow-up.
出处
《中华消化内镜杂志》
2000年第4期214-216,共3页
Chinese Journal of Digestive Endoscopy
