摘要
目的探讨ESWAN序列的R2*值在新生儿局灶性脑白质损伤(PWML)诊断中的价值。材料与方法对22例临床诊断为PWML的新生儿进行头颅常规MRI、DTI、多回波采集的重度 T2*加权的三维梯度回波序列(ESWAN)扫描(早产儿10例,足月儿12例),同时选择22例正常新生儿做对照研究(早产儿10例,足月儿12例),并将病例组及对照组新生儿分别分为早产儿组和足月儿组。分别测量PWML病灶、病灶对侧及正常新生儿病灶对应部位的R2*值,并进行比较。结果早产儿组病灶、病灶对侧及正常早产儿的R2*值分别为7.458±2.463、5.708±2.277、4.024±0.940,足月儿组分别为8.609±2.461、6.621±2.072、5.250±1.526,早产儿组与足月儿组PWML病灶比病灶对侧、正常新生儿的R2*值均高,其中新生儿病灶与正常新生儿间R2*值差异有统计学意义(P<0.05)。结论对比测量R2*值在新生儿PWML的诊断中具有重要的价值。
Objective： To probe the Value of ESWAN-R2＊ value in diagnosis of neonatal punctate white matter lesions （PWML）. Materials and methods： 22 neonates according with the diagnostic standard of PWML were all performed conventional MRI, DTI, ESWAN examination （10 cases of premature, 12 cases of full-term infants）, and 22 cases of normal neonates as controls （10 cases of premature, 12 cases of full-term infants）. The neonates of case group and control group were divided into premature group and full-term group respectively. Measure the R：＊ value of the neonatal PWML lesions, the contralateral side of the lesions, and the same location of lesions in normal neonates, and then compared the values with each other. Results： the R2＊ value of the lesions, the contralateral side of the lesions, and the same location of lesions in normal neonates of the premature group are as follows： 7.458 ± 2.463, 5.708 ± 2.277, 4.024 ± 0.940, the R2＊ value of full-term group＇s are as follows： 8.609 ± 2.461, 6.621 ± 2.072, 5.250 ± 1.526, the R2＊ value of the neonatal PWML are higher than the contralateral side of the lesions and the normal neonates, and the differences between lesions and the normal neonates are significant （P〈0.05）. Conclusion： contrast measurement of ESWAN-R2＊ value has important value in the diagnosis of neonatal PWML.
出处
《磁共振成像》
CAS
CSCD
2013年第3期201-205,共5页
Chinese Journal of Magnetic Resonance Imaging
基金
2010年陕西省社会发展攻关计划项目(2010K15-06-04)
关键词
局灶性脑白质损伤
磁共振成像
缺氧缺血
脑
婴儿
新生
Punctate white matter lesions
Magnetic resonance imaging
Hypoxia- ischemia, brain
Infant, newborn
