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HIV-结核分枝杆菌合并感染致病机理研究 被引量:6

Study of the pathogenic mechanism of HIV and tuberculosis co-infection
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摘要 肺结核是人类最古老的疾病之一,目前仍然威胁着人类的健康。由于采取了积极有效的措施,在发达国家曾一度被控制,但随着人类免疫缺陷病毒(HIV)感染的流行又死灰复燃。HIV合并结核杆菌感染二者相互促进,恶化,并迅速导致死亡,对人类健康和社会经济造成巨大危害。近年来,HIV合并结核杆菌感染的研究日益深入,合并感染的致病机理研究取得新进展。本文对HIV合并结核杆菌感染的致病机理研究进展进行了综述。 Tuberculosis (TB) is one of the oldest human diseases and is still a major infectious disease that greatly threatens human health. Thanks to the implementation of active and effective measures, TB has been controlled in developed countries, but TB has resurged in conjunction with human immunodeficiency virus (HIV) infection. Co-infection encourages the development of both HIV and TB and causes a deterioration in status, rapidly leading to patient death. This is a major threat to human health and socioeconomic conditions. In recent years, studies on HIV and TB co-infection have made some progress; study of its pathogenesis research has yielded many new findings. This paper summarizes the pathogenic mechanism of HIV and TB co-infection.
出处 《中国病原生物学杂志》 CSCD 北大核心 2013年第5期469-472,共4页 Journal of Pathogen Biology
基金 国家自然科学基金项目(No.81060134) 云南省自然科学基金项目(No.2007C069M 2010CD221 2011FB244)
关键词 HIV 结核杆菌 CD4+T细胞 巨噬细胞 肺结核 合并感染 综述 HIV Mycobacterium tuberculosis CD4+T cells macrophage tuberculosis co-infection review
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  • 1Getahun H, Gunneberg C, Granich R, et al. HIV infection-asso- ciated tuberculosis: the epidemiology and the response[J] Clin Infect Dis, 2010, 50(Suppl 3): S201-7.
  • 2叶任高,主编.内科学[M]第6版.北京:人民卫生出版社,2005.57.
  • 3Harrington M. From HIV to tuberculosis and back again: a tale of activism in 2 pandemics [J]. Clin Infect Dis, 2010, 50 (Suppl 3).. S260-6.
  • 4Corbett EL, Watt CJ, Walker N, et al. The growing burden of tuberculosis: global trends and interactions with the HIV epi- demic[J]. Arch Intern Med, 163(9) : 1009-21.
  • 5Aaron L, Saadoun D, Calatroni I, et al. Tuberculosis in HIV-in fected patients: a comprehensive review [J]. Clin Microbiol In- fect, 2004, 10(5) I 388-98.
  • 6Glynn JR, Murray J, Bester A, et al. Effects of duration of HIV infection and secondary tuberculosis transmission on tuberculosis incidence in the South African gold mines[J]. AIDS, 2012, 22 (14): 1859-67.
  • 7Ruker J, Samson M, Doranz BJ, et al. Regions in B-ehe-mokine receptors CCR5 and CCR2b that determine HIV- 1 co-factor spe- cificity[J]. Cell, 1996, 87(3): 437-46.
  • 8Oberlin E, Amara A, Bachelerie F, et al. The CXC cbemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T- cell-l:ne-adapted HIV-I[J]. Nature, 1996, 382(6594): 833-5.
  • 9Brighenti S, Andersson J. Induction and regulation of CD8+ T cells in human tuberculosis and HIV infection [J]. Biochem Bio- phys Research Communications, 2010, 396(1) : 50-7.
  • 10Dye C, Seheele S, Dolin P, et al. Global burden of tuberculosis: estimated incidence, prevalence, andmortality by country. WHO Global Surveillance and Monitoring Project [J]. JAMA, 1999, 282(7) .. 677-86.

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