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糖尿病周围神经病变与血清MBP及S100β相关性分析 被引量：4

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摘要 目的研究髓鞘碱性蛋白(MBP)及S100β蛋白在2型糖尿病患者血清中的表达情况,以探讨MBP及S100β与糖尿病周围神经病变的早期诊断及预后之间的关系。方法 60例2型糖尿病患者分为糖尿病无神经病变组30例和糖尿病神经病变组30例,另选择30例健康体检者作为对照组,取血检测3组血糖、糖化血红蛋白、MBP及S100β蛋白水平,肌电图仪检测运动及感觉神经传导速度。结果糖尿病神经病变组和糖尿病无神经病变组运动神经传导速度和感觉神经传导速度均减慢,且糖尿病神经病变组更明显;空腹血糖、餐后血糖及糖化血红蛋白水平之间均无相关性,3组MBP及S100β含量有显著性差异。结论 2型糖尿病患者血清中MBP及S100β蛋白表达水平变化对糖尿病周围神经病变的诊断有一定的价值。
作者 丛艳 李金萱 秦晓凤
机构地区 江苏省连云港市东方医院
出处 《现代中西医结合杂志》 CAS 2013年第17期1847-1848,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
基金 江苏省连云港市卫生局科研基金资助项目(1127)
关键词 糖尿病周围神经病变 髓鞘碱性蛋白 S100Β蛋白
分类号 R587.2 [医药卫生—内分泌]
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参考文献8

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二级参考文献30

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共引文献14

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现代中西医结合杂志
2013年 第17期

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