摘要
目的研究A型肉毒毒素治疗脑卒中恢复期下肢痉挛的效果。方法将109例脑卒中恢复期患者随机分为治疗组和对照组,两组除予以常规治疗和康复训练外,治疗组对痉挛肌肉加用A型肉毒毒素注射。用改良Ashworth痉挛量表(MAS)、Fugl-Meyer运动功能评定量表(FMA)、Berg平衡量表(BBS)于治疗前,治疗4周、12周后进行评价。结果治疗后各时间点,治疗组MAS、FMA、BBS评分均较对照组改善(P<0.05)。结论局部A型肉毒毒素注射配合系统的康复训练能明显改善痉挛性下肢瘫痪的肌肉痉挛、运动功能和平衡能力。
Objective To study the effect of Botulinum toxin type A （BTX-A） on lower limbs spasticity after stroke. Methods 109 con-valescent patients after stroke were randomly divided into treatment group and the control group. All the patients accepted routine treatment and rehabilitation, the treatment group accepted BTX-A injected in spastic muscles in addition. They were assessed with Fugl-Meyer assess-ment （FMA）, modified Ashworth scale （MAS）, Berg Balance Scale （BBS） before, 4 weeks and 12 weeks after treatment. Results The scores of MAS, BBS and FMA improved more in the treatment group than in the control group （P〈0.05） after treatment. Conclusion Combination of local BTX-A injection can significantly release the lower limbs spasticity, and improve the motor and balance ability for patients after stroke.
出处
《中国康复理论与实践》
CSCD
北大核心
2013年第5期469-471,共3页
Chinese Journal of Rehabilitation Theory and Practice
关键词
脑卒中
下肢痉挛
康复
A型肉毒毒素
stroke
lower limb spasticity
rehabilitation
Botulinum toxin type A
