摘要
自身免疫性甲状腺炎（AIT）的发病受遗传、环境等多重因素影响，其在育龄期女性中的患病率颇高，可增加孕早期流产、早产、死胎、辅助生殖技术（ART）时流产等不良妊娠结局及低体重儿的患病率，其可能与免疫异常、甲状腺功能紊乱以及孕妇高龄等因素有关。其治疗措施主要包括免疫调节、甲状腺功能干预，二者效果如何仍待进一步研究。
A mixture of genetic and environmental factors act in the cause of autoimmunity thyroidi- tis（AIT） ,and women of reproductive age have a high morbidity of it. AIT may increase the incidence of abor- tion in first trimester, premature birth, stillbirth, abortion of assisted reproductive technology and low birth weight infants. Immune disorder, thyroid function disorder, aging might be associated with the poor pregnant outcome. Therefore,immune regulation, thyroid function intervention can be used to deal with it. However, more research about the effectiveness is still needed.
出处
《国际内分泌代谢杂志》
北大核心
2013年第3期170-172,共3页
International Journal of Endocrinology and Metabolism
关键词
妊娠
甲状腺自身免疫
妊娠结局
Pregnancy
Thyroid autoimmunity
Pregnant outcome
