摘要
由硫脲壳聚糖和微量的AgNO3反应得到硫脲壳聚糖-Ag+配合物。通过红外光谱对其结构进行了表征。研究了壳聚糖、硫脲壳聚糖、硫脲壳聚糖-Ag+配合物及AgNO3对大肠杆菌和金黄葡萄球菌的抑菌活性,并测定了其最低抑菌浓度(MIC)和最低杀菌浓度(MBC)。结果表明,硫脲壳聚糖-Ag+配合物的抑菌活性强于壳聚糖和硫脲壳聚糖,且其MIC和MBC均为100 mg/L(游离Ag+含量为0.032 mg/L),低于AgNO3的MIC和MBC(均为120 mg/L)。
Thiourea（TU） chitosan（CTS）-Ag＋ complex was prepared by the reaction of thiourea chitosan with a trace amount of silver ion in homogeneous solution, and was characterized by FT-IR. Antimicrobial activities of CTS, TU-CTS, TU-CTS-Ag＋ complex and AgNO3 were evaluated against E.coli and S.aureus in vitro, and the minimum inhibition concentration（MIC） and the minimum bactericidal concentration（MBC） were determined. The results show that the complex has stronger antimicrobial activities than chitosan and thiourea chitosan. The MIC and MBC of thiourea chitosan Ag＋ complex are both 100 mg/L（free silver ion content 0.032 mg/L）, lower than the MIC and MBC for AgNO3, which are both 120 g/L.
出处
《应用化学》
CAS
CSCD
北大核心
2013年第6期633-637,共5页
Chinese Journal of Applied Chemistry
关键词
壳聚糖
硫脲壳聚糖
抑菌活性
微量Ag+
chitosan thiourea chitosan antimicrobial activity trace amounts of silver iron
