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血清总胆汁酸检测在肝炎后肝硬化患者预后评估中的意义 被引量:4

The clinical significance of total serum bile acid test in evaluation of the prognosis of posthepatitis cirrhosis
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摘要 目的 探讨血清总胆汁酸(TBA)检测在肝炎后肝硬化患者预后评估中的意义。方法 将临床诊断为肝炎后肝硬化患者92例作为观察组,按Child-Pugh评分标准进行分级(A、B、C级),另外选择32例健康体检者作为健康对照组。分别检测研究对象血清总胆汁酸(TBA)水平并比较。结果 观察组血清TBA水平为(84.26±49.03)μmol/L,明显高于健康对照组的(3.52±2.67)μmol/L(t=17.53,P〈0.01);Child-Pugh A、B、C级血清TBA水平依次增高,且差异均有统计学意义(t=3.84、6.21、5.49,均P〈0.05)。结论 血清TBA检测能有助于判断患者肝硬化程度及预后。 Objective To explore the clinical significance of serum total bile acid (TBA) test in evaluation of the prognosis of posthepatitis cirrhosis.Methods 92 patients with posthepatitis cirrhosis were selected as the observation group,and divided into A,B,C groups according to the Child-Pugh grades.32 healthy people were selected as the control group.The level of serum TBA was detected and compared.Results The level of TBA in the observation group was (84.26±49.03)μmol/L,which was higher than that in the control group[(3.52±2.67)μmol/L](t=17.53,P〈0.01). The level of TBA was gradually increased in Child-Pugh grade A,B,C grade,and the differences were statistically significant(t=3.84,6.21,5.49,all P〈0.05).Conclusion TBA test is benefit for the diagnosis and prognosis of posthepatitis cirrhosis.
出处 《中国基层医药》 CAS 2013年第11期1641-1642,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 肝炎 肝硬化 血清总胆汁酸 Hepatitis Cirrhosis Total serum bile acid
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