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七氟烷三种吸入诱导方式对麻醉效果的影响 被引量:2

Influence of sevoflurane by three inhalation induced methods on the anesthetic effect
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摘要 目的 探讨七氟烷三种吸入诱导方式的麻醉效果。方法 将60例在气管插管全麻下行上腹部择期手术的患者根据七氟烷吸入不同分为A组(肺活量呼吸)、B组(潮气量呼吸)和C组(逐渐增加七氟烷浓度),每组20例。A组和B组的七氟烷吸入浓度为9%,C组的七氟烷吸入浓度为4%,均以氧流量3 L/min预充氧气管道。观察并记录在T1(基础指标)、T2(睫毛反射消失)、T3(插管前)、T4(插管2 min时刻)、T5(插管4 min时刻)、T6(插管6 min时刻)各时点患者的心率(HR)、平均血压(MAP)、舒张压(DBP)、收缩压(SBP)和肌松效果数值。结果 A组、B组和C组在不同时间点的SBP、DBP和MAP均得到了抑制(均P〈0.05),并且在时间点T3抑制效果显著(均P〈0.01)。A组、B组和C组在不同时间点HR变化和肌松效果无密切关联(均P〉0.05)。结论 三种七氟烷吸入诱导方式均可使患者的血压降低,并且七氟烷在进行全麻诱导时安全、可靠。 Objective To explore the narcotic effect of three inhalation induced methods of sevoflurane.Methods According to the different inhalation methods of sevoflurane,60 patients with elective upper abdominal surgery under intubation general anesthesia were divided into group A(vital capacity breathing),group B(tidal volume breathing),and group C(gradually increasing the concentration of sevoflurane),each group 20 cases.The sevoflurane concentration of A group and B group was 9%,which of group C was 4%,and oxygen pipeline was prefilled by oxygen flow(3L/min).The heart rate(HR),mean blood pressure(MAP),diastolic blood pressure(DBP) and systolic blood pressure(SBP)values and the effect of muscle relaxants were observed and recorded at T1(basic indicators),T2(eyelash reflex),T3(before intubation),T4(intubation time 2 min),T5(intubation time 4 min),T6(intubation time 6 min).Results The SBP,DBP,and MAP of group A,B and C at different time points were all inhibited(all P〈0.05),and the significant inhibitory effect was at time point T3(all P〈0.01).There was no close correlation between HR changes and the muscle relaxant effect of group A,B and C at different point(all P〉0.05).Conclusion Three kinds of sevoflurane inhalation induction can lower blood pressure,and they are safe,reliable,and able to be accepted by the patients.
出处 《中国基层医药》 CAS 2013年第11期1648-1649,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 七氟烷 麻醉 效果 收缩压 Sevoflurane Anesthetic,effect Systolic blood pressure
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