3[3]Shafritz DA,Lieberman HM.The molecular biology of hepatitis B virus.Annu Rev Med 1984; 35:219-232
4[4]Hoofnagle JH,di Bisceglie AM.The treatment of chronic viral hepatitis.N Engl J Med 1997; 336:347-356
5[5]Chan HL,Leung NW,Hui AY,Wong VW,Liew CT,Chim AM,Chan FK,Hung LC,Lee YT,Tam JS,Lam CW,Sung JJ.A randomized,controlled trial of combination therapy for chronic hepatitis B:comparing pegylated interferon-alpha2b and lamivudine with lamivudine alone.Ann Intern Med 2005;142:240-250
6[6]Mutimer D,Naoumov N,Honkoop P,Marinos G,Ahmed M,de Man R,McPhillips P,Johnson M,Williams R,Elias E,Schalm S.Combination alpha-interferon and lamivudine therapy for alpha-interferon-resistant chronic hepatitis B infection:results of a pilot study.J Hepatol 1998; 28:923-929
7[7]Dienstag JL,Schiff ER,Wright TL,Perrillo RP,Hann HW,Goodman Z,Crowther L,Condreay LD,Woessner M,Rubin M,Brown NA.Lamivudine as initial treatment for chronic hepatitis B in the United States.N Engl J Med 1999; 341:1256-1263
8[8]Schiff ER,Karayalcin S,Grimm I,Perillo RM,Dienstag J,Husa P,Schalm S,Crowther L,Sullivan M,Woessner M,McPhillips P,Brown N,and the international Lamivudine Investigator Group.A placebo controlled study of lamivudine and interferon alpha-2b in patients with chronic hepatitis B who previously failed interferon therapy (abstr).Hepatology 1998; 28:388A
9[9]Porres JC,Mora I,Gutiez J,Bartolome J,Quiroga JA,Bas C,Compernolle C,Ordi J,Chocarro A,Carreno V.Antiviral effect of recombinant gamma interferon in chronic hepatitis B virus infection:a pilot study.Hepatogastroenterology 1988; 35:5-9
10[10]Hayashi Y,Koike K.Interferon inhibits hepatitis B virus replication in a stable expression system of transfected viral DNA.J Virol 1989; 63:2936-2940
