摘要
目的分析150例小细胞肺癌患者外科治疗的预后,评估外科手术在早期小细胞肺癌治疗中的作用及价值。方法 65例小细胞肺癌患者行肺叶切除术和化、放疗(VP方案/钴-60放疗),85例患者行单纯化、放疗(VP方案/钴-60放疗),按照2007年肺癌分期的标准进行分期。结果相对于单纯放、化疗的患者1、3年存活率分别为73%、31%,65例小细胞肺癌患者中,Ⅰ期患者28例,1年及3年生存率分别为100%和82%,Ⅱ期患者37例,1年及3年生存率分别为89%和51%,手术切除辅以术后化、放疗患者的生存期明显延长(P<0.05)。结论对早期的小细胞肺癌患者,手术辅以术后化、放疗方法要优于单纯化、放疗。
Objective To analyse the outcome of 150 patients with small cell lung cancer （SCLC） and to evaluate the role of surgery in treatment of SCLC. Methods Sixty-five pa- tients underwent pulmonary lobectomy combined with chemo/radio （VP/Co-60） therapy, and 85 patients with only ehemo/radio therapy （VP/Co-60）. Clinical stages were carried on ac- cording to the new international staging system （2007 System）. Results Compared to the pa- tients with only ehemo/radio（VP/Co-60） therapy （1-year and 3-year survival rate were 73% and 31% ） , in 65 patients of surgery group, l-year and 3-year survival rate were 100% and 82% in 28 patients in stage I , and rats of those were 89% and 51% in 37 patients in stage Ⅱ. The survival time of the patients with pulmonary lobectomy combined with chemo/radio- therapy was significantly prolonged. Conclusion The therapy of surgery treatment combined with chemo/radio（VP/Co-60） therapy is better than chemo/radio（VP/Co-60） only for the pa- tients with SCLC in the early stage.
出处
《哈尔滨医科大学学报》
CAS
北大核心
2013年第2期181-183,共3页
Journal of Harbin Medical University
关键词
小细胞肺癌
手术治疗
化疗
放疗
small cell lung cancer
surgical treatment
chemotherapy
raidotherapy
