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高原红细胞增多症的诊治进展 被引量:5

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摘要 高原红细胞增多症(HAPC)是一类因机体对高海拔缺氧环境适应失代偿而导致的红细胞(RBC)异常增生的慢性高原病,其发病机理与缺氧后机体神经内分泌系统的异常密切相关,亦与群体先天的易感基因存在联系。HAPC的治疗重点是针对促红细胞生成素(EPO)的升高和RBC增殖应用相应的药物。同时,支持治疗、改善其并发症的药物治疗以及中成药物治疗也十分重要。针对HAPC的治疗,立足于现有的对症支持、降低RBC、改善缺氧等基础之上,一些新的药物如植物类激素、EPO靶向治疗是未来HAPC治疗的重要方向。本文就近年来国内外关于HAPc诊疗的研究进展,综述如下。
出处 《国际输血及血液学杂志》 CAS 2013年第3期260-263,共4页 International Journal of Blood Transfusion and Hematology
基金 “十一五”国家科技支撑计划项目(2009BA185802)
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参考文献26

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