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SIRT1对心衰的保护作用研究进展 被引量：7

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摘要 心力衰竭是多种心血管疾病最终的共同通路，其发病率高，预后差．是目前引起大家关注的严重健康问题之一。衰竭心脏呈现出复杂的表型，包括心肌细胞减少、纤维化增加、对应激反应性降低、心肌能量储备丢失、心肌收缩功能障碍等。越来越多的证据表明，表观遗传修饰形成了细胞内各种反应的分子基质。
作者 郭鑫 杨俊
机构地区 三峡大学心血管病研究所 宜昌市中心人民医院心内科
出处 《实用医学杂志》 CAS 北大核心 2013年第11期1877-1878,共2页 The Journal of Practical Medicine
基金 国家自然科学基金项目(编号:81170133 81200088) 湖北省自然科学基金计划项目(编号:2011CDB179)
关键词 SIRT1 保护作用 心衰 收缩功能障碍 表观遗传修饰 心血管疾病 共同通路 心力衰竭
分类号 R541.6 [医药卫生—心血管疾病]
  • 相关文献

参考文献19

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二级参考文献22

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共引文献44

同被引文献74

  • 1吴超.中医药治疗缺血性心脏病的研究进展[J].内蒙古中医药,2009(2):92-93. 被引量：4
  • 2刘红,汪芳,黄一玲,王杨,段兵,边文彦,李一石.健康人群血清NT-proBNP浓度水平评估[J].中国实验诊断学,2007,11(3):287-289. 被引量：10
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实用医学杂志
2013年 第11期

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