摘要
目的:探讨青年直肠癌患者的临床病理特征。方法:回顾性分析2002年1月-2012年1月10年收治、行手术治疗的279例直肠癌患者的临床病理特征并进行回顾性分析,以40岁为界限,分为青年组(年龄≤40岁)和非青年组(年龄>40岁)。结果:肿瘤下缘距肛门距离≤7cm的比例占73.5%(205/279),病理类型以腺癌为主,占79.6%(222/279),细胞分化多呈高分化(33.3%,93/279)和中分化(43.0%,120/279),肝转移比率为10.0%(28/279),手术方式以根治术为主,占85.7%(239/279)。青年组患者直肠癌比率为15.1%(42/279),青年组患者黏液腺癌+印戒细胞癌比例、细胞低分化比例、Dukes D分期比例、淋巴结转移比例、肝转移比例及姑息切除手术和单纯结肠造瘘,均显著高于非青年组(P<0.01)。青年组患者肿瘤下缘距肛门距离≤7cm的比例为81.0%(34/42),高于非青年组,差异不显著(P>0.05)。结论:青年直肠癌患者具有直肠癌组织低分化、恶性程度高、易发生淋巴结转移和肝转移、就诊时分期偏晚、根治手术比例较低等临床病理特征。
Objective：To explore the clinicopathological features for the young people with rectal carcinoma.Methods：The data of 279 cases treated from January 2002 to January,of which were divided into two groups as age at onset：juvenile group（≤40 years old） and senile group（40 years old）,were analyzed retrospectively.Results：The ratio for the patients with distance less than 7cm away from the anal verge acounted to 73.5%（205/279）,adenocarcinoma being the major histological type 79.6%（222/279）,so as well and middle differentiated（33.3%,93/279;43.0%,120/279） and radical resection of rectal carcinoma,with the liver metastasis ratio was 10%（28/279）.The ratio of juvenile rectal cancer patients was 15.1%（42/279）,and the ratio of mucinous carcinomas and signet ring cell carcinoma,poor differentiation,Dukes D staging,lymphatic metastasis,liver metastasis,palliative resection and colostomy in juvenile group was sifnifantly higher than that in senile group,except for the ratio of distance less than 7 cm away from the anal verge.Conclusion：The main clinical features of juvenile patients with rectal carcinoma are poor differentiation,high malignant degree,being prone to lymph nodes metastasis,advanced stage at onset and lower radical resection ratio.
出处
《现代肿瘤医学》
CAS
2013年第6期1296-1298,共3页
Journal of Modern Oncology
关键词
直肠癌
青年
回顾性分析
rectal carcinoma
juvenile
clinicopathological features
