摘要
子宫内膜癌是最常见的女性生殖系统恶性肿瘤之一,约25%发生在绝经前妇女,治疗方法为全子宫和双附件切除,这使患者失去了生育功能。近年来,处于生育年龄的子宫内膜癌患者症状出现相对早、分化程度好、期别早,且大多数为性激素依赖型(Ⅰ型),预后较好。文献报道了较多早期子宫内膜癌患者保守治疗成功的案例,使希望未来生育的早期年轻患者保留了生育功能。但在治疗过程中需选择适合人群,要个体化治疗并严密监测。现就早期年轻子宫内膜癌患者保留生育功能的可行性以及相关问题做一综述。
Endometrial cancer is one of the most common malignant tumors of the female reproductive system.Approximately 25% of patients with endometrial cancer are premenopausal.In the past,treatment is the removal of the entire uterus and double attachment that patients lose their reproductive function.Currently,the child-bearing age in patients with endometrial cancer appear symptoms relatively early,histological grade better,clinical stage early,most of the sex hormone-dependent（type Ⅰ）have a better prognosis.The literature has reported many successful cases of early endometrial cancer patients with conservative treatment and young patients that who hope the future fertility preserve the reproductive function.However,in the course of treatment the appropriate crowd must be selected.Fertility treatment should be individualized,and close surveillance is required during treatment.Fertility-sparing management of young patients with endometrial cancer in the feasibility and related issues were reviewed.
出处
《现代肿瘤医学》
CAS
2013年第6期1401-1404,共4页
Journal of Modern Oncology
关键词
子宫内膜癌
保留生育功能
孕激素治疗
endometrial cancer
fertility-sparing management
progestin therapy
