摘要
目的：观察纯中药制剂甲眼消合并他巴唑治疗甲状腺机能亢进症（简称甲亢）突眼的临床疗效。方法：43例患者随机分为两组，治疗组（31例）予以甲眼消、他巴唑治疗，对照组（12例）予以强的松、他巴唑治疗。3个月为1个疗程，均观察1个疗程。观察两组治疗前后甲亢突眼的临床症状、眼征、甲状腺激素水平的改善情况及在不良反应发生率上的差异。结果：治疗组总有效率（80．6％），显著高于对照组（50．0％，P＜0．05）；而且治疗组在减少眼球突出度方面明显优于对照组（P＜0．05）；在提高视力、减少平视睑裂高度与降低血清T3、T4含量方面与对照组作用相近（P＞0．05）；在改善临床症状、减少副作用方面以治疗组为佳。结论：甲眼消治疗甲亢突眼疗效肯定。
To study the therapeutic effect of Jiayanxiao (JYX) on thyrotoxic exophthalmos. [WT4”HZ]Methods: Forty three patients were divided randomly into two groups, the 31 Patients in the treated group were treated with JYX plus tapazole, and the 12 patients in the control group were treated with prednisone plus tapazole. The therapeutic course of both groups was 3 months. The symptoms, eye signs, thyroxin level, and other routine laboratory parameters as well as the adverse effect of the therapy were observed and compared between two groups. [WT4”HZ]Results: The total effective rate in the treated group was 80.6%, which was obviously higher than that in the control group (50.0%, P<0 05). Effect of the treated group in lowering degree of exophthalmos was superior to that of the control group. Effects in elevating vision, decreasing palpebral fissure altitude and lowering serum T 3, T 4 contents in the two groups were similar (P>0 05). Moreover, the treated group showed better efficacy in improving clinical symptoms with less adverse effect. [WT4”HZ]Conclusion: The therapeutic effect of JYX in treating thyrotoxic exophthalmos is ensured.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2000年第6期433-435,共3页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
甲状腺机能亢进症突眼
甲眼消
他巴唑
治疗
thyrotoxic exophthalmos
traditional Chinese medicine therapy
Jiayanxiao
