摘要
本文建立了大鼠脑缺血及再灌注模型 ,并对缺血以及缺血后再灌注不同时间的血液触变性进行了实验研究 ,用 Huang's方程拟合实验曲线以得到各组血液的 5个触变性参数。结果表明 :缺血以及缺血后再灌注不同时间 ,对血液触变性参数有明显的影响。缺血过程中 ,τ0 和 μ的值随着缺血时间的增加逐渐降低 ,缺血再灌注 1小时的 τ0 和 μ明显大于缺血期的值 ,τ0 也高于正常值 ,随着再灌注时间的增加 ,τ0 逐渐回落至正常血液水平 ,同时
The rat model of cerebral ischemia and reperfusion was constracted in the experiment to study the thixotropic properties of whole rat blood.Five thixotropic parameters were obtained from the experiment curve line,fitted with Huang's equations.The results showed:significant differences existed between the thixotroptic parameters and for the length of time of cerebral ischemia with reperfusion.Along and increaing of cerebral ischemia time,the values of τ\-0 and μ declined gradually.After an hour of reperfusion,the values of τ\-0 and μ were significantly greater than these just only of cerebral ischemia.And the value of τ\-0 was even higher than the normal one.With the increase of reperfusion time, the value of τ\-0 returned to normal level gradually,and at the same time,the value of μ is also decreased gradually
出处
《北京生物医学工程》
EI
2000年第2期101-104,共4页
Beijing Biomedical Engineering
基金
北京市自然科学基金!( 3 982 0 0 5)
北京市教委基金
北京市青年科技骨干培养基金
关键词
脑缺血
再灌注损伤
血液触变性
血液流变学
Cerebral ischemia, Cerebral ischemia and reperfusion, Thixotropic properties
