摘要
脑卒中发病率、死亡率、致残率和复发率高,缺血性脑卒中约占80%。传统风险因素只能解释部分发病原因,遗传因素引起了人们的关注。卒中的遗传学研究众多,但尚缺乏令人信服的结论。本文对目前缺血性脑卒中的遗传研究主要进展进行述评,以供深入研究与探讨。
Stroke is a huge public health concern because of its high morbidity, mortality, disability and recur- rence, and up to 80% are ischemic in origin. The traditional risk factors explain only approximately 60% of ischemic stroke (IS). Genetic background might contribute to a predisposition to IS. Although, a number of genetic studies on IS were conducted, the results were disappointing. The present review mainly focus on the progress of genetic research in IS.
出处
《西部医学》
2013年第6期803-806,共4页
Medical Journal of West China
基金
国家自然科学基金项目(81271317)