摘要
目的出血性膀胱炎是造血干细胞移植后主要并发症之一,探讨感染与出血性膀胱炎的关系,从而指导对出血性膀胱炎患者的临床护理,预防感染的发生。方法对36例造血干细胞移植后合并与非合并出血性膀胱炎患者分为两组,每组各18例,比较两组患者人类白细胞抗原(HLA)配型、性别、感染因素包括巨细胞病毒、内毒素、真菌G试验结果。结果 HLA配型不完全相合者出血性膀胱炎(HC)相对高发,而与性别无相关性;与巨细胞感染有相关性(P=0.038);与内毒素感染(P=0.5)、与真菌感染均G试验无相关性(P=0.301)。结论造血干细胞移植后合并出血性膀胱炎的患者,与巨细胞病毒感染有很大相关性,应做好预防护理工作。
OBJECTIVE The haemorrhagic cystitis （HC） is one of major complications after hematopoietic stem cell transplantation. This research explored the correlation between the infections and haemorrhagic cystitis after hem-atopoietic stem cell transplantation so as to guide the clinical nursing of the HC patients and to prevent the infec-tions. METHODS A total of 36 HC patients, who underwent hematopoietic stem cell transplantation, were divided into two groups with 18 cases in each. The risk factors for HC were explored. The HLA match, gender, factors for infections including the CMV, endoxin and fungal G trial were compared between the two groups. RESULTS The patients with incomplete HLA match had the higher rate of HC, there was no difference in the gender; there was correlation between the. HC and CMV infection （P=0. 038）; there was no correlation between the HC and the endotoxin （P= 0. 5） ; there was no correlation between the HC and fungal infection G trial （P = 0. 301）. CONCLUSION The HC in the patients who underwent the hematopoietic Stem cell transplantation is closely related to the CMV infections, it is necessary to take the prevention and nursing measures.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第11期2591-2592,共2页
Chinese Journal of Nosocomiology
关键词
造血干细胞移植
出血性膀胱炎
感染
护理
H ematopoietic stem cell transplantation
Hemorrhagic cystitis
Infection
Nursing care
