摘要
新近发现山西省柳林县部分地区属轻度缺碘地区:水碘2.4μg/L,居民尿碘40.3μg/g·Cr,地甲肿患病率8.5％。该地区目前尚未施用碘剂防治。我们于1988年8～11月对该地区土生土长的1012名0～12岁儿童进行亚临床克汀病筛查,发现该地区亚克汀患病率为1.98％,亚克汀患病率随年龄增加而增高,趋势x^2检验有十分显著统计学意义。男女性别之比为1∶1.1。对筛出的20例亚克汀病患者采用1∶1配对调查,发现体重、身高、头围、内眦、外眦、瞳距等躯体发育指标均无明显差异。智能发育方面,亚克汀儿童抬头平均晚一个月,认人平均晚两个月,有显著的统计学意义。 采用相同的程序对缺碘已补碘十年的相邻县临县6个村1028名0～12岁儿童筛查,该县生活条件、文化水平和柳林县极相似,亚临床克汀病患病率为0.68％,与柳林县相比,有十分显著的统计学意义,说明补碘确实是防治亚克汀病的有力措施。
A new mild iodine deficiency area was found in Liuling County, Shanxi Province recently. Water iodine was 2.4μg/l. Average urinary iodine excretion of residents was 40.3μg/g. cr. Prevalence of endemic goiter was 8.58%. A total of 1012 children (0-12 years) were tested. The results showed that prevalence of subclinic cretinism was 1.98%. It was increased with age (trend x2=18.98 P<0.01). The boy-girl ratio was 1:1.1. The results of matched case-control study showed there were no significant differences among weight, height, circumference of head, length between medial palpebral commissures, lateral palpebral commissures and pupils. The time of raising head in subclinic creatinism was one month later than the control group. The time of recognizing persons in subclinic creatinism was 2 months later than the control, which showed significant statistical differences.
In the 6 villages of Lin County, where the living conditions was almost the same as those in Liuling County, 1028 children (0-12 years) were tested using the same procedure. The prevalence of subclinic creatinism was 0.68%. Compared with Liuling County, it was significantly different. It proved that iodine supplement was effective for prevention of subclinic creatinism.
出处
《地方病通报》
1991年第3期78-81,共4页
Endemic Diseases Bulletin
关键词
克汀病
筛查
碘缺乏
Mild iodine deficiency
Subclinic cretinism
Screening
