摘要
[目的]探讨恶性肿瘤患者贫血的发生情况及其相关危险因素。[方法]回顾性分析我院综合科2010年1月至12月收治的986例恶性肿瘤患者,进行单因素和多因素Logistic回归分析。[结果]所有患者中,男性573例(58.2%),女性413例(41.8%),死亡124例,贫血669例,贫血发生率为67.8%。Ⅰ级295例(44.1%),Ⅱ级218例(32.6%),Ⅲ级87例(13.0%),Ⅳ级69例(10.3%)。胃肠道肿瘤贫血发生率最高为77.5%。单因素分析显示,年龄、肿瘤分期、抗肿瘤治疗、肿瘤类型、合并出血与恶性肿瘤贫血的发生有关,具有统计学意义(P<0.05)。多因素Logistic回归分析显示,合并出血、临床分期、抗肿瘤治疗与贫血发生密切相关。[结论]恶性肿瘤患者贫血发生率较高;肿瘤分期、合并出血和抗肿瘤治疗是恶性肿瘤贫血发生的危险因素。
[Purpose] To explore the occurrence of anemia in patients with malignancy and the related risk factors. [Methods] A retrospective analysis was performed in 986 patients with malignancy from January to December （2010） by single factor analysis and multivarite logistic analysis. [Results] Among all the cases,there were 573（58.2%） in male,413（41.8%） in female and 124 patients died of cancer. Anemia occurred in 669 cases account for 67.8% of all the cases with malignancy. Based on anemia grading,295 cases（44.1%） was grade Ⅰ,218（32.6%） grade Ⅱ,87（13.0%） grade Ⅲ,69 （10.3%） grade Ⅳ . Gastrointestinal cancer was the highest occurence of anemia with 77.5% .Univariant analysis demonstrated that anemia was correlated to age,grade,anti-neoplastic therapy,tumor type and combined bleeding,with statistic significance （P0.05）. Multivarite logistic analysis showed that bleeding, and anti-neoplastic therapy were significantly correlated to anemia. [Conclusion] Patients with malignancy have a high occurence of anemia. Tumor stage,bleeding and anti-neoplastic therapy are the risk factors of anemia in patients with malignancy.
出处
《中国肿瘤》
CAS
2013年第5期403-405,共3页
China Cancer
关键词
肿瘤
癌性贫血
危险因素
neoplasm
cancer-related anemia
risk factor
