摘要
目的观察左卡尼汀联合促红细胞生成素治疗MHD患者肾性贫血及营养状态的疗效。方法将肾性贫血患者62例分成2组,每组31例。两组同时于血液透析后注射促红细胞生成素,每周150 U/kg。在此基础上,治疗组于每次血液透析后静脉注射左卡尼汀2.0 g,2次/周,疗程12周。结果治疗组血红蛋白、红细胞压积水平、白蛋白、总蛋白水平显著高于对照组(P<0.05)。结论左卡尼汀能显著提高促红细胞生成素对血液透析患者贫血的疗效,并且改善患者的营养状况。
Objective To investigate the effects of levocarnitine combined with erythropoietin on anemia and nutritional status of patients with maintenance hemodialysis. Methods 62 uremic patients undergoing maintenance he- modialysis were divided into 2 groups:treatment group and control group,31 cases in each group. Every time at the end of the hemodialysis treatment, the patients of the two groups were given erythropoietin, 150 U/kg weekly. At the same time, the treatment group received intravenous injection of levocarnitine, 2. 0 g, twice a week, the treatment lasted 12 weeks. Results The levels of plasma total protein, albumin,hemoglobin and blood hematocrit of treatment group were significantly higher than those of control group ( P 〈 0.05 ). Condusion Levocarnitine can improve the anemia and nutritional status of patients with maintenance hemodialysis.
出处
《实用药物与临床》
CAS
2013年第5期397-398,共2页
Practical Pharmacy and Clinical Remedies