摘要
目的:观察中药复方对肺癌化疗患者临床并发症改善效果,探讨改善机理。方法:对本院自2010年12月—2013年3月收治肺癌化疗患者进行研究,依据治疗方法分为治疗组(61例)和对照组(42例),治疗组在化疗的同时给予中药复方治疗,对照组单纯进行化疗治疗。观察患者TNF-α、IL-2、IL-4和IL-10水平变化,比较临床并发症发生率。结果:治疗组患者血清TNF-α和IL-2水平较对照组有所升高,而血清IL-4和IL-10水平有所降低,患者并发症状发生率较低,两组比较,差异有统计学意义(P<0.05)。结论:中药复方能够提升患者血清TNF-a和IL-2水平,降低IL-4和IL-10水平,调节患者Th1/Th2平衡;改善患者因化疗出现的并发症状,临床疗效甚佳。
Objective：To improve the effect of Chinese herbal compound on clinical complications of patients with lung cancer, looking forward the mechanism. Methods：From December 2010 to March 2013, lung cancer patients treated with chemotherapy, were divided into a treatment group （n = 61 ）and control group（42 cases） according to the treatment method. The treatment group was given chemotherapy at the same time of traditional Chinese medicine compound treatment;the control group was treated with chemotherapy treatment. TNF - ct, IL - 2, IL - 4 and IL - 10 levels were observed, the clinical incidence of complications was compared. Results ：The serum TNF - omnd IL - 2 levels were increased in treatment group compared with those in the control group,levels of IL -4 and IL - 10 were decreased. There was a low incidence of complications in the two groups, and the difference was statistically significant （ P 〈 0. 05 ）. Conclusion ： Chinese herbal compound can enhance the serum TNF - αand IL - 2 levels,lower IL -4 and IL - 10 levels, regulate patients Thl/Th2 balance;improve patients due to chemotherapy concurrent symptoms, and the clinical efficacy is very good.
出处
《辽宁中医杂志》
CAS
2013年第6期1151-1152,共2页
Liaoning Journal of Traditional Chinese Medicine
关键词
中药复方
肺癌
化疗
并发症
Chinese herbal compound
lung cancer
chemotherapy
complications
